NMR Studies of Nucleic Acids as Drug Targets

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NMR Studies of Nucleic Acids as Drug Targets

Nogalamycin is a member of the anthracycline family of antitumour antibiotics. These are potent cytotoxic agents and are routinely used in cancer chemotherapy. Though nogalamycin is clinically insignificant, it does exhibit three distinct types of non-covalent binding to DNA. Since most other ant...

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Bibliographic Details
Main Author:	Gallagher, Cathal T
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2004
Subjects:	NMR DNA Molecular Dynamics Simulation Quadruplex Hairpin Loop Hydration Patterns.
Online Access:	https://eprints.nottingham.ac.uk/10082/

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