Anti-inflammatory activity of roots of Achyranthes aspera
This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn. (Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet gr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis
2009
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| Subjects: | |
| Online Access: | http://eprints.intimal.edu.my/200/ http://eprints.intimal.edu.my/200/1/1.pdf |
| _version_ | 1848766419481657344 |
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| author | S., Vijaya Kumar P., Sankar R., Varatharajan |
| author_facet | S., Vijaya Kumar P., Sankar R., Varatharajan |
| author_sort | S., Vijaya Kumar |
| building | INTI Institutional Repository |
| collection | Online Access |
| description | This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn.
(Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the
carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet granuloma test
(chronic inflammatory model). The alcohol extract showed significant suppressed granuloma formation.
Collectively, these data demonstrate promising anti-inflammatory activity against both acute and chronic
inflammation. In addition, inhibition of prostaglandins and bradykinins may play a role. This study reveal-
ing the promising anti-inflammatory activity of Achyranthes aspera roots has been carried out scientifically
for the first time. |
| first_indexed | 2025-11-14T11:50:51Z |
| format | Article |
| id | intimal-200 |
| institution | INTI International University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T11:50:51Z |
| publishDate | 2009 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | intimal-2002016-04-25T05:36:52Z http://eprints.intimal.edu.my/200/ Anti-inflammatory activity of roots of Achyranthes aspera S., Vijaya Kumar P., Sankar R., Varatharajan QR Microbiology This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn. (Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet granuloma test (chronic inflammatory model). The alcohol extract showed significant suppressed granuloma formation. Collectively, these data demonstrate promising anti-inflammatory activity against both acute and chronic inflammation. In addition, inhibition of prostaglandins and bradykinins may play a role. This study reveal- ing the promising anti-inflammatory activity of Achyranthes aspera roots has been carried out scientifically for the first time. Taylor & Francis 2009 Article PeerReviewed text en http://eprints.intimal.edu.my/200/1/1.pdf S., Vijaya Kumar and P., Sankar and R., Varatharajan (2009) Anti-inflammatory activity of roots of Achyranthes aspera. Pharmaceutical Biology, 47 (10). pp. 973-975. ISSN 1744-5116 10.1080/13880200902967979 |
| spellingShingle | QR Microbiology S., Vijaya Kumar P., Sankar R., Varatharajan Anti-inflammatory activity of roots of Achyranthes aspera |
| title | Anti-inflammatory activity of roots of Achyranthes
aspera |
| title_full | Anti-inflammatory activity of roots of Achyranthes
aspera |
| title_fullStr | Anti-inflammatory activity of roots of Achyranthes
aspera |
| title_full_unstemmed | Anti-inflammatory activity of roots of Achyranthes
aspera |
| title_short | Anti-inflammatory activity of roots of Achyranthes
aspera |
| title_sort | anti-inflammatory activity of roots of achyranthes
aspera |
| topic | QR Microbiology |
| url | http://eprints.intimal.edu.my/200/ http://eprints.intimal.edu.my/200/ http://eprints.intimal.edu.my/200/1/1.pdf |