Anti-inflammatory activity of roots of Achyranthes aspera
This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn. (Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet gr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis
2009
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| Subjects: | |
| Online Access: | http://eprints.intimal.edu.my/200/ http://eprints.intimal.edu.my/200/1/1.pdf |
| Summary: | This study investigated the anti-inflammatory potential of the alcohol extract of Achyranthes aspera Linn.
(Amaranthaceae) in Wistar rats after oral administration (50, 100, and 200 mg/kg). This was done using the
carrageenan-induced paw edema method (acute inflammatory model) and cotton pellet granuloma test
(chronic inflammatory model). The alcohol extract showed significant suppressed granuloma formation.
Collectively, these data demonstrate promising anti-inflammatory activity against both acute and chronic
inflammation. In addition, inhibition of prostaglandins and bradykinins may play a role. This study reveal-
ing the promising anti-inflammatory activity of Achyranthes aspera roots has been carried out scientifically
for the first time. |
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