Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform

One of the main challenges faced by researchers in the field of microfluidic compact disc (CD) platforms is the control of liquid movement and sequencing during spinning. This paper presents a novel microfluidic valve based on the principle of liquid equilibrium on a rotating CD. The proposed l...

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Main Authors: Al-Faqheri, Wisam, Ibrahim, Fatimah, Thio, Tzer Hwai Gilbert, Arof, Hamzah, Madou, Marc
Format: Article
Language:English
Published: IEEE 2013
Subjects:
Online Access:http://eprints.intimal.edu.my/172/
http://eprints.intimal.edu.my/172/1/Novel%20Liquid%20Equilibrium%20Valving%20on%20Centrifugal%20Microfluidic%20CD.pdf
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author Al-Faqheri, Wisam
Ibrahim, Fatimah
Thio, Tzer Hwai Gilbert
Arof, Hamzah
Madou, Marc
author_facet Al-Faqheri, Wisam
Ibrahim, Fatimah
Thio, Tzer Hwai Gilbert
Arof, Hamzah
Madou, Marc
author_sort Al-Faqheri, Wisam
building INTI Institutional Repository
collection Online Access
description One of the main challenges faced by researchers in the field of microfluidic compact disc (CD) platforms is the control of liquid movement and sequencing during spinning. This paper presents a novel microfluidic valve based on the principle of liquid equilibrium on a rotating CD. The proposed liquid equilibrium valve operates by balancing the pressure produced by the liquids in a source and a venting chamber during spinning. The valve does not require external forces or triggers, and is able to regulate burst frequencies with high accuracy. In this work, we demonstrate that the burst frequency can be significantly raised by making just a small adjustment of the liquid height in the vent chamber. Finally, the proposed valve ng method can be used separately or combined with other valving methods in advance microfluidic processes.
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spelling intimal-1722016-10-06T05:39:10Z http://eprints.intimal.edu.my/172/ Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform Al-Faqheri, Wisam Ibrahim, Fatimah Thio, Tzer Hwai Gilbert Arof, Hamzah Madou, Marc TA Engineering (General). Civil engineering (General) TJ Mechanical engineering and machinery One of the main challenges faced by researchers in the field of microfluidic compact disc (CD) platforms is the control of liquid movement and sequencing during spinning. This paper presents a novel microfluidic valve based on the principle of liquid equilibrium on a rotating CD. The proposed liquid equilibrium valve operates by balancing the pressure produced by the liquids in a source and a venting chamber during spinning. The valve does not require external forces or triggers, and is able to regulate burst frequencies with high accuracy. In this work, we demonstrate that the burst frequency can be significantly raised by making just a small adjustment of the liquid height in the vent chamber. Finally, the proposed valve ng method can be used separately or combined with other valving methods in advance microfluidic processes. IEEE 2013 Article PeerReviewed text en http://eprints.intimal.edu.my/172/1/Novel%20Liquid%20Equilibrium%20Valving%20on%20Centrifugal%20Microfluidic%20CD.pdf Al-Faqheri, Wisam and Ibrahim, Fatimah and Thio, Tzer Hwai Gilbert and Arof, Hamzah and Madou, Marc (2013) Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform. 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). p. 5512. ISSN 1094-687X 10.1109/EMBC.2013.6610797
spellingShingle TA Engineering (General). Civil engineering (General)
TJ Mechanical engineering and machinery
Al-Faqheri, Wisam
Ibrahim, Fatimah
Thio, Tzer Hwai Gilbert
Arof, Hamzah
Madou, Marc
Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform
title Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform
title_full Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform
title_fullStr Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform
title_full_unstemmed Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform
title_short Novel Liquid Equilibrium Valving on Centrifugal Microfluidic CD Platform
title_sort novel liquid equilibrium valving on centrifugal microfluidic cd platform
topic TA Engineering (General). Civil engineering (General)
TJ Mechanical engineering and machinery
url http://eprints.intimal.edu.my/172/
http://eprints.intimal.edu.my/172/
http://eprints.intimal.edu.my/172/1/Novel%20Liquid%20Equilibrium%20Valving%20on%20Centrifugal%20Microfluidic%20CD.pdf