Graphene synthesis and antibody immobilization techniques for iImmunosensors

The principle of antigen–antibody interaction is exploited for immunosensor development. Over the years, immunosensors have been fabricated for different applications, and the fabrication process has benefited from the use of nanomaterials. Graphene, a single-atom-thick layer of carbon, has been use...

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Bibliographic Details
Main Authors: Shohibuddin, Ihda Uswatun Shalihah, Barthasarathy, Piravin Raj, Wan Salim, Wan Wardatul Amani
Format: Book Chapter
Language:English
Published: Springer Singapore 2020
Subjects:
Online Access:http://irep.iium.edu.my/82605/
http://irep.iium.edu.my/82605/1/82605_Graphene%20synthesis%20and%20antibody.pdf
Description
Summary:The principle of antigen–antibody interaction is exploited for immunosensor development. Over the years, immunosensors have been fabricated for different applications, and the fabrication process has benefited from the use of nanomaterials. Graphene, a single-atom-thick layer of carbon, has been used to coat the sensing electrodes of immunosensors; antibodies are then immobilized onto the graphene-modified electrodes to produce graphene-based immunosensors. Here, we describe several techniques for producing graphene and its derivatives. We also focus on approaches for antibody immobilization on these graphene-modified electrodes.