Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial

Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compa...

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Main Authors: Muhd Helmi, Muhd Alwi, Hussain, Suhaimi, Bachok, Norsaadah
Format: Proceeding Paper
Language:English
English
Published: 2019
Subjects:
Online Access:http://irep.iium.edu.my/82430/
http://irep.iium.edu.my/82430/1/20190801144129409.pdf
http://irep.iium.edu.my/82430/7/CONTINUOUS%20GLUCOSE%20MONITORING%20SYSTEM%20VS%20SELF-MONITORING%20BLOOD%20GLUCOSE.pdf
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author Muhd Helmi, Muhd Alwi
Hussain, Suhaimi
Bachok, Norsaadah
author_facet Muhd Helmi, Muhd Alwi
Hussain, Suhaimi
Bachok, Norsaadah
author_sort Muhd Helmi, Muhd Alwi
building IIUM Repository
collection Online Access
description Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between continuous glucose monitoring system (CGMS) and self-monitoring blood glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children.
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language English
English
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spelling iium-824302020-08-28T01:49:31Z http://irep.iium.edu.my/82430/ Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial Muhd Helmi, Muhd Alwi Hussain, Suhaimi Bachok, Norsaadah RJ Pediatrics Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between continuous glucose monitoring system (CGMS) and self-monitoring blood glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children. 2019-10-10 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/82430/1/20190801144129409.pdf application/pdf en http://irep.iium.edu.my/82430/7/CONTINUOUS%20GLUCOSE%20MONITORING%20SYSTEM%20VS%20SELF-MONITORING%20BLOOD%20GLUCOSE.pdf Muhd Helmi, Muhd Alwi and Hussain, Suhaimi and Bachok, Norsaadah (2019) Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial. In: Diabetes Asia 2019 Conference, 10th -13th October 2019, Hotel Istana, Kuala Lumpur. (Unpublished)
spellingShingle RJ Pediatrics
Muhd Helmi, Muhd Alwi
Hussain, Suhaimi
Bachok, Norsaadah
Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial
title Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial
title_full Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial
title_fullStr Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial
title_full_unstemmed Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial
title_short Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (RoSEC): a randomized controlled trial
title_sort continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes mellitus children (rosec): a randomized controlled trial
topic RJ Pediatrics
url http://irep.iium.edu.my/82430/
http://irep.iium.edu.my/82430/1/20190801144129409.pdf
http://irep.iium.edu.my/82430/7/CONTINUOUS%20GLUCOSE%20MONITORING%20SYSTEM%20VS%20SELF-MONITORING%20BLOOD%20GLUCOSE.pdf