High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults
Background: Metabolic syndrome is a major risk factor for cardiovascular diseases. It is increasingly common among young adults. High- sensitivity C-reactive protein (HsCRP) has been recognised as a cardiovascular biomarker. This study evaluated the association between HsCRP and metabolic syndrome i...
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| Format: | Proceeding Paper |
| Language: | English English English |
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2020
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| Online Access: | http://irep.iium.edu.my/82122/ http://irep.iium.edu.my/82122/1/E-poster%20Hypertension%20Busan%202020.mp4 http://irep.iium.edu.my/82122/2/Hypertension%20BUSAN%202020_Certificate%20of%20presentation_Wan%20Fatein%20Nabeila%20Wan%20Omar.png http://irep.iium.edu.my/82122/13/%5BHypertension%20Busan%202020%5D%20Abstract%20Book.pdf |
| _version_ | 1848789240811356160 |
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| author | Wan Omar, Wan Fatein Nabeila Abdullah, Aszrin A.Talib, Norlelawati Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah |
| author_facet | Wan Omar, Wan Fatein Nabeila Abdullah, Aszrin A.Talib, Norlelawati Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah |
| author_sort | Wan Omar, Wan Fatein Nabeila |
| building | IIUM Repository |
| collection | Online Access |
| description | Background: Metabolic syndrome is a major risk factor for cardiovascular diseases. It is increasingly common among young adults. High- sensitivity C-reactive protein (HsCRP) has been recognised as a cardiovascular biomarker. This study evaluated the association between HsCRP and metabolic syndrome in Malaysian young adult population.
Method: The study was a comparative observational cross-sectional study performed in Kuantan, Pahang, Malaysia. A total of 240 young adults age 18 to 45 years were assessed for anthropometric measurements, blood pressure, fasting blood glucose and fasting lipids. Metabolic syndrome was defined using the revised Joint Interim Statement Criteria. Subjects with HsCRP protein that exceeded 10 ng/ml were excluded from subsequent analysis.
Result: The prevalence of metabolic syndrome was 26.25% and no difference was seen between genders (p = 0.175). Mean high- sensitivity C-reactive protein level was 2.79 mg/l and not significantly different between genders (p = 0.807). HsCRP was significantly higher in subjects with metabolic syndrome compared to those without metabolic syndrome (p = 0.001). Significant association between increasing number of metabolic syndrome components present with HsCRP level (p < 0.05), with stronger association observed in females (p = 0.002).
Conclusion: HsCRP is positively associated with metabolic syndrome in Malaysian young adults, with stronger association in females. HsCRP could serve as an adjunct to predict MetS in young adults. Prospective study is required to confirm the causality of increasing HsCRP on metabolic syndrome components. |
| first_indexed | 2025-11-14T17:53:35Z |
| format | Proceeding Paper |
| id | iium-82122 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T17:53:35Z |
| publishDate | 2020 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-821222021-01-07T06:20:23Z http://irep.iium.edu.my/82122/ High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults Wan Omar, Wan Fatein Nabeila Abdullah, Aszrin A.Talib, Norlelawati Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah QH426 Genetics QP Physiology RC627 Specialties of Internal Medicine-Metabolic Diseases Background: Metabolic syndrome is a major risk factor for cardiovascular diseases. It is increasingly common among young adults. High- sensitivity C-reactive protein (HsCRP) has been recognised as a cardiovascular biomarker. This study evaluated the association between HsCRP and metabolic syndrome in Malaysian young adult population. Method: The study was a comparative observational cross-sectional study performed in Kuantan, Pahang, Malaysia. A total of 240 young adults age 18 to 45 years were assessed for anthropometric measurements, blood pressure, fasting blood glucose and fasting lipids. Metabolic syndrome was defined using the revised Joint Interim Statement Criteria. Subjects with HsCRP protein that exceeded 10 ng/ml were excluded from subsequent analysis. Result: The prevalence of metabolic syndrome was 26.25% and no difference was seen between genders (p = 0.175). Mean high- sensitivity C-reactive protein level was 2.79 mg/l and not significantly different between genders (p = 0.807). HsCRP was significantly higher in subjects with metabolic syndrome compared to those without metabolic syndrome (p = 0.001). Significant association between increasing number of metabolic syndrome components present with HsCRP level (p < 0.05), with stronger association observed in females (p = 0.002). Conclusion: HsCRP is positively associated with metabolic syndrome in Malaysian young adults, with stronger association in females. HsCRP could serve as an adjunct to predict MetS in young adults. Prospective study is required to confirm the causality of increasing HsCRP on metabolic syndrome components. 2020-08-07 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/82122/1/E-poster%20Hypertension%20Busan%202020.mp4 application/pdf en http://irep.iium.edu.my/82122/2/Hypertension%20BUSAN%202020_Certificate%20of%20presentation_Wan%20Fatein%20Nabeila%20Wan%20Omar.png application/pdf en http://irep.iium.edu.my/82122/13/%5BHypertension%20Busan%202020%5D%20Abstract%20Book.pdf Wan Omar, Wan Fatein Nabeila and Abdullah, Aszrin and A.Talib, Norlelawati and Ab Rahman, Jamalludin and Mohd Shah, Azarisman Shah (2020) High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults. In: Hypertension Busan 2020 in conjunction with the 52nd Scientific Meeting of The Korean Society of Hypertension, Bexco, Busan , Republic of Korea. http://khypertension.kr |
| spellingShingle | QH426 Genetics QP Physiology RC627 Specialties of Internal Medicine-Metabolic Diseases Wan Omar, Wan Fatein Nabeila Abdullah, Aszrin A.Talib, Norlelawati Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| title | High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| title_full | High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| title_fullStr | High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| title_full_unstemmed | High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| title_short | High sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| title_sort | high sensitivity c-reactive protein: uncovering the metabolic delinquent in young adults |
| topic | QH426 Genetics QP Physiology RC627 Specialties of Internal Medicine-Metabolic Diseases |
| url | http://irep.iium.edu.my/82122/ http://irep.iium.edu.my/82122/ http://irep.iium.edu.my/82122/1/E-poster%20Hypertension%20Busan%202020.mp4 http://irep.iium.edu.my/82122/2/Hypertension%20BUSAN%202020_Certificate%20of%20presentation_Wan%20Fatein%20Nabeila%20Wan%20Omar.png http://irep.iium.edu.my/82122/13/%5BHypertension%20Busan%202020%5D%20Abstract%20Book.pdf |