Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women

Abstract: Objective: C.striatus has been suggested to have antioxidant and anti-inflammatory properties for wound healing. This study was conducted to determine the level of Total Antioxidant Status (TAS) and the effectiveness of oral supplementation of C.striatus extract in post Lower Segment Caesa...

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Main Authors: Shafii, Noorazliyana, Omar, Julia, Kuttulebbai Naina Mohamed Salam, Sirajudeen, Yaacob, Najib Majdi, Abdullah, Mohamed Rusli
Format: Article
Language:English
Published: Japan Health Sciences University & Japan International Cultural Exchange Foundation 2020
Subjects:
Online Access:http://irep.iium.edu.my/81958/
http://irep.iium.edu.my/81958/7/IMJ%20liyana%20paper%20april2020.pdf
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author Shafii, Noorazliyana
Omar, Julia
Kuttulebbai Naina Mohamed Salam, Sirajudeen
Yaacob, Najib Majdi
Abdullah, Mohamed Rusli
author_facet Shafii, Noorazliyana
Omar, Julia
Kuttulebbai Naina Mohamed Salam, Sirajudeen
Yaacob, Najib Majdi
Abdullah, Mohamed Rusli
author_sort Shafii, Noorazliyana
building IIUM Repository
collection Online Access
description Abstract: Objective: C.striatus has been suggested to have antioxidant and anti-inflammatory properties for wound healing. This study was conducted to determine the level of Total Antioxidant Status (TAS) and the effectiveness of oral supplementation of C.striatus extract in post Lower Segment Caesarean Section (LSCS) patients during wound healing. Design: This was a randomized; double blinded, placebo-controlled study among post LSCS women conducted in Department of Obstetric and Gynaecology, Hospital Universiti Sains Malaysia from March 2010 to December 2012. Material and Methods: A total of 39 patients from C.striatus and 34 patients from placebo group were included in this study. After randomization, the treatment group consumed 500 mg of freeze dried C.striatus extract daily while the placebo group consumed 500 mg of placebo (maltodextrin) daily for 6 weeks. For each subject, venous bloods for TAS were taken postoperatively at day 1, day 3, week 2, week 4 and week 6. Repeated measure for analysis of variance (ANOVA) was used to determine the changes of TAS between and within both groups throughout the 6 weeks intervention. Results: The result suggested an increment of TAS level within C.striatus group from second week postoperative onwards which might involve in the enhancement of wound healing. Conclusion: The administration of C.striatus extract has beneficial effect during wound healing by enhancing the process in post-operative LSCS women.
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institution International Islamic University Malaysia
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spelling iium-819582021-01-11T04:48:19Z http://irep.iium.edu.my/81958/ Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women Shafii, Noorazliyana Omar, Julia Kuttulebbai Naina Mohamed Salam, Sirajudeen Yaacob, Najib Majdi Abdullah, Mohamed Rusli R Medicine (General) Abstract: Objective: C.striatus has been suggested to have antioxidant and anti-inflammatory properties for wound healing. This study was conducted to determine the level of Total Antioxidant Status (TAS) and the effectiveness of oral supplementation of C.striatus extract in post Lower Segment Caesarean Section (LSCS) patients during wound healing. Design: This was a randomized; double blinded, placebo-controlled study among post LSCS women conducted in Department of Obstetric and Gynaecology, Hospital Universiti Sains Malaysia from March 2010 to December 2012. Material and Methods: A total of 39 patients from C.striatus and 34 patients from placebo group were included in this study. After randomization, the treatment group consumed 500 mg of freeze dried C.striatus extract daily while the placebo group consumed 500 mg of placebo (maltodextrin) daily for 6 weeks. For each subject, venous bloods for TAS were taken postoperatively at day 1, day 3, week 2, week 4 and week 6. Repeated measure for analysis of variance (ANOVA) was used to determine the changes of TAS between and within both groups throughout the 6 weeks intervention. Results: The result suggested an increment of TAS level within C.striatus group from second week postoperative onwards which might involve in the enhancement of wound healing. Conclusion: The administration of C.striatus extract has beneficial effect during wound healing by enhancing the process in post-operative LSCS women. Japan Health Sciences University & Japan International Cultural Exchange Foundation 2020-04-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/81958/7/IMJ%20liyana%20paper%20april2020.pdf Shafii, Noorazliyana and Omar, Julia and Kuttulebbai Naina Mohamed Salam, Sirajudeen and Yaacob, Najib Majdi and Abdullah, Mohamed Rusli (2020) Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women. International Medical Journal, 27 (2). pp. 148-150. ISSN 13412051 https://seronjihou.com/imj27-2/
spellingShingle R Medicine (General)
Shafii, Noorazliyana
Omar, Julia
Kuttulebbai Naina Mohamed Salam, Sirajudeen
Yaacob, Najib Majdi
Abdullah, Mohamed Rusli
Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women
title Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women
title_full Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women
title_fullStr Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women
title_full_unstemmed Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women
title_short Effect of oral supplementation of Channa striatus extract on total antioxidant status during wound healing in post Lower Segment Caesarean Section women
title_sort effect of oral supplementation of channa striatus extract on total antioxidant status during wound healing in post lower segment caesarean section women
topic R Medicine (General)
url http://irep.iium.edu.my/81958/
http://irep.iium.edu.my/81958/
http://irep.iium.edu.my/81958/7/IMJ%20liyana%20paper%20april2020.pdf