Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases

In recent years, natural products, which originate from plants, animals, and fungi, together with their bioactive compounds have been intensively explored and studied for their therapeutic potentials for various diseases such as cardiovascular, diabetes, hypertension, reproductive, cancer, and neuro...

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Main Authors: Mohd Sairazi, Nur Shafika, Kuttulebbai Naina Mohamed Salam, Sirajudeen
Format: Article
Language:English
English
Published: Hindawi Limited 2020
Subjects:
Online Access:http://irep.iium.edu.my/81899/
http://irep.iium.edu.my/81899/1/2020%20neuro%20review%20paper%2014.2.2020.pdf
http://irep.iium.edu.my/81899/7/Scopus%20-%20Natural%20Products%20and%20Their%20Bioactive%20Compounds.pdf
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author Mohd Sairazi, Nur Shafika
Kuttulebbai Naina Mohamed Salam, Sirajudeen
author_facet Mohd Sairazi, Nur Shafika
Kuttulebbai Naina Mohamed Salam, Sirajudeen
author_sort Mohd Sairazi, Nur Shafika
building IIUM Repository
collection Online Access
description In recent years, natural products, which originate from plants, animals, and fungi, together with their bioactive compounds have been intensively explored and studied for their therapeutic potentials for various diseases such as cardiovascular, diabetes, hypertension, reproductive, cancer, and neurodegenerative diseases. Neurodegenerative diseases, including Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are characterized by the progressive dysfunction and loss of neuronal structure and function that resulted in the neuronal cell death. Since the multifactorial pathological mechanisms are associated with neurodegeneration, targeting multiple mechanisms of actions and neuroprotection approach, which involves preventing cell death and restoring the function to damaged neurons, could be promising strategies for the prevention and therapeutic of neurodegenerative diseases. Natural products have emerged as potential neuroprotective agents for the treatment of neurodegenerative diseases. .is review focused on the therapeutic potential of natural products and their bioactive compounds to exert a neuroprotective effect on the pathologies of neurodegenerative diseases.
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spelling iium-818992021-01-11T04:50:51Z http://irep.iium.edu.my/81899/ Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases Mohd Sairazi, Nur Shafika Kuttulebbai Naina Mohamed Salam, Sirajudeen R Medicine (General) In recent years, natural products, which originate from plants, animals, and fungi, together with their bioactive compounds have been intensively explored and studied for their therapeutic potentials for various diseases such as cardiovascular, diabetes, hypertension, reproductive, cancer, and neurodegenerative diseases. Neurodegenerative diseases, including Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are characterized by the progressive dysfunction and loss of neuronal structure and function that resulted in the neuronal cell death. Since the multifactorial pathological mechanisms are associated with neurodegeneration, targeting multiple mechanisms of actions and neuroprotection approach, which involves preventing cell death and restoring the function to damaged neurons, could be promising strategies for the prevention and therapeutic of neurodegenerative diseases. Natural products have emerged as potential neuroprotective agents for the treatment of neurodegenerative diseases. .is review focused on the therapeutic potential of natural products and their bioactive compounds to exert a neuroprotective effect on the pathologies of neurodegenerative diseases. Hindawi Limited 2020-02-14 Article PeerReviewed application/pdf en http://irep.iium.edu.my/81899/1/2020%20neuro%20review%20paper%2014.2.2020.pdf application/pdf en http://irep.iium.edu.my/81899/7/Scopus%20-%20Natural%20Products%20and%20Their%20Bioactive%20Compounds.pdf Mohd Sairazi, Nur Shafika and Kuttulebbai Naina Mohamed Salam, Sirajudeen (2020) Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases. Evidence-Based Complementary and Alternative Medicine, 2020. pp. 1-30. ISSN 1741-427X https://www.hindawi.com/journals/ecam/2020/6565396/ 10.1155/2020/6565396
spellingShingle R Medicine (General)
Mohd Sairazi, Nur Shafika
Kuttulebbai Naina Mohamed Salam, Sirajudeen
Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
title Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
title_full Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
title_fullStr Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
title_full_unstemmed Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
title_short Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
title_sort natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases
topic R Medicine (General)
url http://irep.iium.edu.my/81899/
http://irep.iium.edu.my/81899/
http://irep.iium.edu.my/81899/
http://irep.iium.edu.my/81899/1/2020%20neuro%20review%20paper%2014.2.2020.pdf
http://irep.iium.edu.my/81899/7/Scopus%20-%20Natural%20Products%20and%20Their%20Bioactive%20Compounds.pdf