Model comparison of estimated glomerular filtration rate for acute kidney injury in intensive care unit
Acute kidney injury (AKI) is common in critically ill patients and often associated with higher mortality. It is commonly diagnosed using plasma creatinine, a fluid eglomerular filtration. In this study, we analysed the highly nonlinear and complex behaviour within human systems of estimating glomer...
| Main Authors: | , , , , , |
|---|---|
| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
IOP Publishing Ltd.
2020
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/81882/ http://irep.iium.edu.my/81882/1/Model_comparison_of_estimated_glomerular_filtratio.pdf http://irep.iium.edu.my/81882/7/Scopus%20-%20Model%20comparison%20of%20estimated%20glomerular%20filtration%20rate%20for%20acute%20kidney.pdf |
| _version_ | 1848789198349271040 |
|---|---|
| author | Dzaharudin, Fatimah Jamaludin, Ummu Kulthum Md Ralib, Azrina Mat Nor, Mohd Basri Tumian, Afidalina Ismail, Amelia Ritahani |
| author_facet | Dzaharudin, Fatimah Jamaludin, Ummu Kulthum Md Ralib, Azrina Mat Nor, Mohd Basri Tumian, Afidalina Ismail, Amelia Ritahani |
| author_sort | Dzaharudin, Fatimah |
| building | IIUM Repository |
| collection | Online Access |
| description | Acute kidney injury (AKI) is common in critically ill patients and often associated with higher mortality. It is commonly diagnosed using plasma creatinine, a fluid eglomerular filtration. In this study, we analysed the highly nonlinear and complex behaviour within human systems of estimating glomerular filtration rate in critically ill patients to estimate AKI outcome by developing an application program that describes various numerical mathematical models estimated glomerular filtration rate (eGFR). The program was developed to collect numerous clinical patient data and perform computations of the governing equations that may provide clinicians with rapid estimation of GFR which allow prediction of recovery or worsening of renal function at bedside. Data collection using the application program was conducted at the intensive care unit in Kuantan, Malaysia from January to August 2016. It was found that the eGFR by CKD-EPI shows the best correlation with kinetic GFR (keGFR) equations compared to other mathematical methods for Malaysian ICU patients. It is endeavoured that more patient data would be collected using this mobile application, to develop a more accurate GFR estimation model suitable for Asian populations since creatinine based equations are often derived based on white populations. |
| first_indexed | 2025-11-14T17:52:54Z |
| format | Proceeding Paper |
| id | iium-81882 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:52:54Z |
| publishDate | 2020 |
| publisher | IOP Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-818822020-10-20T02:54:23Z http://irep.iium.edu.my/81882/ Model comparison of estimated glomerular filtration rate for acute kidney injury in intensive care unit Dzaharudin, Fatimah Jamaludin, Ummu Kulthum Md Ralib, Azrina Mat Nor, Mohd Basri Tumian, Afidalina Ismail, Amelia Ritahani RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid Acute kidney injury (AKI) is common in critically ill patients and often associated with higher mortality. It is commonly diagnosed using plasma creatinine, a fluid eglomerular filtration. In this study, we analysed the highly nonlinear and complex behaviour within human systems of estimating glomerular filtration rate in critically ill patients to estimate AKI outcome by developing an application program that describes various numerical mathematical models estimated glomerular filtration rate (eGFR). The program was developed to collect numerous clinical patient data and perform computations of the governing equations that may provide clinicians with rapid estimation of GFR which allow prediction of recovery or worsening of renal function at bedside. Data collection using the application program was conducted at the intensive care unit in Kuantan, Malaysia from January to August 2016. It was found that the eGFR by CKD-EPI shows the best correlation with kinetic GFR (keGFR) equations compared to other mathematical methods for Malaysian ICU patients. It is endeavoured that more patient data would be collected using this mobile application, to develop a more accurate GFR estimation model suitable for Asian populations since creatinine based equations are often derived based on white populations. IOP Publishing Ltd. 2020-06-05 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/81882/1/Model_comparison_of_estimated_glomerular_filtratio.pdf application/pdf en http://irep.iium.edu.my/81882/7/Scopus%20-%20Model%20comparison%20of%20estimated%20glomerular%20filtration%20rate%20for%20acute%20kidney.pdf Dzaharudin, Fatimah and Jamaludin, Ummu Kulthum and Md Ralib, Azrina and Mat Nor, Mohd Basri and Tumian, Afidalina and Ismail, Amelia Ritahani (2020) Model comparison of estimated glomerular filtration rate for acute kidney injury in intensive care unit. In: 5th International Conference on Mechanical Engineering Research 2019, 30 July 2019 - 31 July 2019, Vistana Hotel, Kuantan, Pahang. https://iopscience.iop.org/article/10.1088/1757-899X/788/1/012030 10.1088/1757-899X/788/1/012030 |
| spellingShingle | RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid Dzaharudin, Fatimah Jamaludin, Ummu Kulthum Md Ralib, Azrina Mat Nor, Mohd Basri Tumian, Afidalina Ismail, Amelia Ritahani Model comparison of estimated glomerular filtration rate for acute kidney injury in intensive care unit |
| title | Model comparison of estimated glomerular filtration rate for
acute kidney injury in intensive care unit |
| title_full | Model comparison of estimated glomerular filtration rate for
acute kidney injury in intensive care unit |
| title_fullStr | Model comparison of estimated glomerular filtration rate for
acute kidney injury in intensive care unit |
| title_full_unstemmed | Model comparison of estimated glomerular filtration rate for
acute kidney injury in intensive care unit |
| title_short | Model comparison of estimated glomerular filtration rate for
acute kidney injury in intensive care unit |
| title_sort | model comparison of estimated glomerular filtration rate for
acute kidney injury in intensive care unit |
| topic | RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid |
| url | http://irep.iium.edu.my/81882/ http://irep.iium.edu.my/81882/ http://irep.iium.edu.my/81882/ http://irep.iium.edu.my/81882/1/Model_comparison_of_estimated_glomerular_filtratio.pdf http://irep.iium.edu.my/81882/7/Scopus%20-%20Model%20comparison%20of%20estimated%20glomerular%20filtration%20rate%20for%20acute%20kidney.pdf |