Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature
Background: The aim of this study was to provide a scoping review of the impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia. Methods: A scoping review was conducted using pre-defined search terms in three scientific d...
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| Format: | Article |
| Language: | English English |
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Dove Medical Press
2020
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| Online Access: | http://irep.iium.edu.my/81774/ http://irep.iium.edu.my/81774/1/Elnaem2020%20impact-of-pharmacist-led-interventions-on-medication-adherence.pdf http://irep.iium.edu.my/81774/7/81774_Impact%20of%20pharmacist-led%20interventions_scopus.pdf |
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| author | Elnaem, Mohamed Hassan Abdelaziz Rosely, Nur Fatin Al-hifany, Abdullah Elrggal, Mahmoud Cheema, Ejaz |
| author_facet | Elnaem, Mohamed Hassan Abdelaziz Rosely, Nur Fatin Al-hifany, Abdullah Elrggal, Mahmoud Cheema, Ejaz |
| author_sort | Elnaem, Mohamed Hassan Abdelaziz |
| building | IIUM Repository |
| collection | Online Access |
| description | Background: The aim of this study was to provide a scoping review of the impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia. Methods: A scoping review was conducted using pre-defined search terms in three scientific databases, including Google Scholar, ScienceDirect, and PubMed. A multi-stage screening process that considered relevancy, publication year (2009– 2019), English language, and article type (original research) was followed. Review articles, meta-analysis studies, and conference proceedings were excluded. Data charting was done in an iterative process using a study-specific extraction form. Results: Of the initially identified 681 studies, 17 studies with 136,026 patients were included in the review. Of these, 16 were randomized controlled trials, while the remaining study was a retrospective cohort study. The majority of pharmacist-led interventions were face-to-face counseling sessions (n=8), followed by remote- or telephone-based interventions (n=5) and multi-faceted interventions (n=4). The majority of the studies (n=7) used self-reported adherence measures and pharmacy refill records (n=8) to measure the rate of adherence to prescribed medications. Eleven of the included studies reported a statistically significant (P< 0.05) impact on medication adherence. Overall, twelve studies assessed the effect of the interventions on the clinical outcome measures; of these, only four studies were associated with significant impact. Conclusion: Pharmacist-led interventions were associated with improved patients’ adherence to their medications but were less likely to be consistently associated with the attainment of clinical outcomes. Face-to-face counseling was the most commonly used intervention; while, the multi-faceted interventions were more likely to be effective in improving the overall outcome measures. The rigorous design of targeted interventions with more frequent follow-ups, careful consideration of the involved medications, and patients’ characteristics could increase the effectiveness of these interventions. |
| first_indexed | 2025-11-14T17:52:41Z |
| format | Article |
| id | iium-81774 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:52:41Z |
| publishDate | 2020 |
| publisher | Dove Medical Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-817742022-07-15T02:22:15Z http://irep.iium.edu.my/81774/ Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature Elnaem, Mohamed Hassan Abdelaziz Rosely, Nur Fatin Al-hifany, Abdullah Elrggal, Mahmoud Cheema, Ejaz R Medicine (General) RS Pharmacy and materia medica Background: The aim of this study was to provide a scoping review of the impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia. Methods: A scoping review was conducted using pre-defined search terms in three scientific databases, including Google Scholar, ScienceDirect, and PubMed. A multi-stage screening process that considered relevancy, publication year (2009– 2019), English language, and article type (original research) was followed. Review articles, meta-analysis studies, and conference proceedings were excluded. Data charting was done in an iterative process using a study-specific extraction form. Results: Of the initially identified 681 studies, 17 studies with 136,026 patients were included in the review. Of these, 16 were randomized controlled trials, while the remaining study was a retrospective cohort study. The majority of pharmacist-led interventions were face-to-face counseling sessions (n=8), followed by remote- or telephone-based interventions (n=5) and multi-faceted interventions (n=4). The majority of the studies (n=7) used self-reported adherence measures and pharmacy refill records (n=8) to measure the rate of adherence to prescribed medications. Eleven of the included studies reported a statistically significant (P< 0.05) impact on medication adherence. Overall, twelve studies assessed the effect of the interventions on the clinical outcome measures; of these, only four studies were associated with significant impact. Conclusion: Pharmacist-led interventions were associated with improved patients’ adherence to their medications but were less likely to be consistently associated with the attainment of clinical outcomes. Face-to-face counseling was the most commonly used intervention; while, the multi-faceted interventions were more likely to be effective in improving the overall outcome measures. The rigorous design of targeted interventions with more frequent follow-ups, careful consideration of the involved medications, and patients’ characteristics could increase the effectiveness of these interventions. Dove Medical Press 2020-07-20 Article PeerReviewed application/pdf en cc_by http://irep.iium.edu.my/81774/1/Elnaem2020%20impact-of-pharmacist-led-interventions-on-medication-adherence.pdf application/pdf en http://irep.iium.edu.my/81774/7/81774_Impact%20of%20pharmacist-led%20interventions_scopus.pdf Elnaem, Mohamed Hassan Abdelaziz and Rosely, Nur Fatin and Al-hifany, Abdullah and Elrggal, Mahmoud and Cheema, Ejaz (2020) Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature. Journal of Multidisciplinary Healthcare, 13. pp. 635-645. ISSN 1178-2390 https://www.dovepress.com/impact-of-pharmacist-led-interventions-on-medication-adherence-and-cli-peer-reviewed-article-JMDH 10.2147/JMDH.S257273 |
| spellingShingle | R Medicine (General) RS Pharmacy and materia medica Elnaem, Mohamed Hassan Abdelaziz Rosely, Nur Fatin Al-hifany, Abdullah Elrggal, Mahmoud Cheema, Ejaz Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature |
| title | Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature |
| title_full | Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature |
| title_fullStr | Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature |
| title_full_unstemmed | Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature |
| title_short | Impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: A scoping review of published literature |
| title_sort | impact of pharmacist-led interventions on medication adherence and clinical outcomes in patients with hypertension and hyperlipidemia: a scoping review of published literature |
| topic | R Medicine (General) RS Pharmacy and materia medica |
| url | http://irep.iium.edu.my/81774/ http://irep.iium.edu.my/81774/ http://irep.iium.edu.my/81774/ http://irep.iium.edu.my/81774/1/Elnaem2020%20impact-of-pharmacist-led-interventions-on-medication-adherence.pdf http://irep.iium.edu.my/81774/7/81774_Impact%20of%20pharmacist-led%20interventions_scopus.pdf |