Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress
Over the past two decades, supercritical fluid technology has emerged as one of the most important technologies applied in many fields such as cosmetic, food and pharmaceutical. Supercritical fluid extraction process offers numerous advantages such as easy, effective, inexpensive, high quality of so...
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| Format: | Article |
| Language: | English English |
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Association of Pharmaceutical Teachers of India
2020
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| Online Access: | http://irep.iium.edu.my/81598/ http://irep.iium.edu.my/81598/13/81598_Supercritical%20Fluid%20Technology%20and%20its_fulltext.pdf http://irep.iium.edu.my/81598/1/81598_Supercritical%20fluid%20technology_SCOPUS.pdf |
| _version_ | 1848789156813078528 |
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| author | Liew, Kai Bin Janakiraman, Ashok Kumar Abd Razak, Fashli Syafiq Helal Uddin, A.B.M. Sarker, Md. Zaidul Islam Ming, Long Chiau Goh, Bey Hing |
| author_facet | Liew, Kai Bin Janakiraman, Ashok Kumar Abd Razak, Fashli Syafiq Helal Uddin, A.B.M. Sarker, Md. Zaidul Islam Ming, Long Chiau Goh, Bey Hing |
| author_sort | Liew, Kai Bin |
| building | IIUM Repository |
| collection | Online Access |
| description | Over the past two decades, supercritical fluid technology has emerged as one of the most important technologies applied in many fields such as cosmetic, food and pharmaceutical. Supercritical fluid extraction process offers numerous advantages such as easy, effective, inexpensive, high quality of solute extraction and environmentally friendly. This mini-review describes the fundamentals of supercritical fluid technology, the function of supercritical fluid as solvent and anti-solvent, mechanism of supercritical fluid, advantages and disadvantages and revisit the application of supercritical fluid technology in pharmaceutical sciences. In-depth discussion with recent examples of extraction of natural products, particle design in drug delivery, preparation on pharmaceutical powder, drug solubilization, inclusion complex, polymer impregnation, liposomal formulations, purification and polymorphism as well as drug extraction analysis are also presented. Key aspects and processing considerations of supercritical fluid technologies are reviewed to assist scientists to generate other related experimental works. © 2020, Association of Pharmaceutical Teachers of India. All rights reserved. |
| first_indexed | 2025-11-14T17:52:15Z |
| format | Article |
| id | iium-81598 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:52:15Z |
| publishDate | 2020 |
| publisher | Association of Pharmaceutical Teachers of India |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-815982022-11-07T02:20:56Z http://irep.iium.edu.my/81598/ Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress Liew, Kai Bin Janakiraman, Ashok Kumar Abd Razak, Fashli Syafiq Helal Uddin, A.B.M. Sarker, Md. Zaidul Islam Ming, Long Chiau Goh, Bey Hing RM Therapeutics. Pharmacology Over the past two decades, supercritical fluid technology has emerged as one of the most important technologies applied in many fields such as cosmetic, food and pharmaceutical. Supercritical fluid extraction process offers numerous advantages such as easy, effective, inexpensive, high quality of solute extraction and environmentally friendly. This mini-review describes the fundamentals of supercritical fluid technology, the function of supercritical fluid as solvent and anti-solvent, mechanism of supercritical fluid, advantages and disadvantages and revisit the application of supercritical fluid technology in pharmaceutical sciences. In-depth discussion with recent examples of extraction of natural products, particle design in drug delivery, preparation on pharmaceutical powder, drug solubilization, inclusion complex, polymer impregnation, liposomal formulations, purification and polymorphism as well as drug extraction analysis are also presented. Key aspects and processing considerations of supercritical fluid technologies are reviewed to assist scientists to generate other related experimental works. © 2020, Association of Pharmaceutical Teachers of India. All rights reserved. Association of Pharmaceutical Teachers of India 2020-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/81598/13/81598_Supercritical%20Fluid%20Technology%20and%20its_fulltext.pdf application/pdf en http://irep.iium.edu.my/81598/1/81598_Supercritical%20fluid%20technology_SCOPUS.pdf Liew, Kai Bin and Janakiraman, Ashok Kumar and Abd Razak, Fashli Syafiq and Helal Uddin, A.B.M. and Sarker, Md. Zaidul Islam and Ming, Long Chiau and Goh, Bey Hing (2020) Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress. Indian Journal of Pharmaceutical Education and Research, 54 (2 (April-June)). s1-s11. ISSN 0019-5464 http://ijper.org/sites/default/files/IndJPhaEdRes-54-2s-1.pdf 10.5530/ijper.54.2s.56 |
| spellingShingle | RM Therapeutics. Pharmacology Liew, Kai Bin Janakiraman, Ashok Kumar Abd Razak, Fashli Syafiq Helal Uddin, A.B.M. Sarker, Md. Zaidul Islam Ming, Long Chiau Goh, Bey Hing Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| title | Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| title_full | Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| title_fullStr | Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| title_full_unstemmed | Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| title_short | Supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| title_sort | supercritical fluid technology and its pharmaceutical applications: a revisit with two decades of progress |
| topic | RM Therapeutics. Pharmacology |
| url | http://irep.iium.edu.my/81598/ http://irep.iium.edu.my/81598/ http://irep.iium.edu.my/81598/ http://irep.iium.edu.my/81598/13/81598_Supercritical%20Fluid%20Technology%20and%20its_fulltext.pdf http://irep.iium.edu.my/81598/1/81598_Supercritical%20fluid%20technology_SCOPUS.pdf |