Genetics of malocclusion: a review

Malocclusion is one of the most common craniofacial problems observed worldwide. Affected individuals suffer not only from aesthetic concerns but also from functional problems, such as with mastication and pronunciation. The prevalence of malocclusion in East Asians is higher than in other races. Re...

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Main Authors: Mokhtar@Makhtar, Khairani Idah, Abu Bakar, Noraini, Md Ali @ Tahir, Aisyah Hanani
Format: Article
Language:English
Published: Kulliyyah of Dentistry, International Islamic University Malaysia 2020
Subjects:
Online Access:http://irep.iium.edu.my/80999/
http://irep.iium.edu.my/80999/1/80999_Genetics%20of%20malocclusion.pdf
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author Mokhtar@Makhtar, Khairani Idah
Abu Bakar, Noraini
Md Ali @ Tahir, Aisyah Hanani
author_facet Mokhtar@Makhtar, Khairani Idah
Abu Bakar, Noraini
Md Ali @ Tahir, Aisyah Hanani
author_sort Mokhtar@Makhtar, Khairani Idah
building IIUM Repository
collection Online Access
description Malocclusion is one of the most common craniofacial problems observed worldwide. Affected individuals suffer not only from aesthetic concerns but also from functional problems, such as with mastication and pronunciation. The prevalence of malocclusion in East Asians is higher than in other races. Reports have shown besides environmental factors, there is association between certain types of malocclusion with specific genes. Positive association of mandibular prognathism has been implicated to genes such as Matrilin-1; while mutation in DUSP6 has also been shown to contribute to the incidence of malocclusion. This review aimed to briefly discuss the involvement of other additional genes such as MYO1H and PAX9 in the incidence of malocclusion as observed from our local institution.
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institution International Islamic University Malaysia
institution_category Local University
language English
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publishDate 2020
publisher Kulliyyah of Dentistry, International Islamic University Malaysia
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spelling iium-809992020-06-23T09:08:24Z http://irep.iium.edu.my/80999/ Genetics of malocclusion: a review Mokhtar@Makhtar, Khairani Idah Abu Bakar, Noraini Md Ali @ Tahir, Aisyah Hanani RK Dentistry Malocclusion is one of the most common craniofacial problems observed worldwide. Affected individuals suffer not only from aesthetic concerns but also from functional problems, such as with mastication and pronunciation. The prevalence of malocclusion in East Asians is higher than in other races. Reports have shown besides environmental factors, there is association between certain types of malocclusion with specific genes. Positive association of mandibular prognathism has been implicated to genes such as Matrilin-1; while mutation in DUSP6 has also been shown to contribute to the incidence of malocclusion. This review aimed to briefly discuss the involvement of other additional genes such as MYO1H and PAX9 in the incidence of malocclusion as observed from our local institution. Kulliyyah of Dentistry, International Islamic University Malaysia 2020 Article PeerReviewed application/pdf en http://irep.iium.edu.my/80999/1/80999_Genetics%20of%20malocclusion.pdf Mokhtar@Makhtar, Khairani Idah and Abu Bakar, Noraini and Md Ali @ Tahir, Aisyah Hanani (2020) Genetics of malocclusion: a review. International Journal of Orofacial and Health Sciences, 1 (1). pp. 4-10. ISSN 2716-5434 http://www.iium.edu.my/media/55204/IJOHS%20Volume%201%20Issue%201.pdf
spellingShingle RK Dentistry
Mokhtar@Makhtar, Khairani Idah
Abu Bakar, Noraini
Md Ali @ Tahir, Aisyah Hanani
Genetics of malocclusion: a review
title Genetics of malocclusion: a review
title_full Genetics of malocclusion: a review
title_fullStr Genetics of malocclusion: a review
title_full_unstemmed Genetics of malocclusion: a review
title_short Genetics of malocclusion: a review
title_sort genetics of malocclusion: a review
topic RK Dentistry
url http://irep.iium.edu.my/80999/
http://irep.iium.edu.my/80999/
http://irep.iium.edu.my/80999/1/80999_Genetics%20of%20malocclusion.pdf