Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl

Entada spiralis Ridl. which is locally known as Sintok or Beluru is a woody climber with a characteristic spiral stem. The stem bark is traditionally used as natural shampoo and body wash among Malays due to its high content of saponins and its medicinal properties. The methanol extract of the stem...

Full description

Bibliographic Details
Main Authors: Mat So'ad, Siti Zaiton, Harun, Aiza, Mohd Hassan, Norazian, Che Mohd Ramli, Neni Kartini
Format: Proceeding Paper
Language:English
Published: 2011
Subjects:
Online Access:http://irep.iium.edu.my/8023/
http://irep.iium.edu.my/8023/4/iirie2011.pdf
_version_ 1848776940599640064
author Mat So'ad, Siti Zaiton
Harun, Aiza
Mohd Hassan, Norazian
Che Mohd Ramli, Neni Kartini
author_facet Mat So'ad, Siti Zaiton
Harun, Aiza
Mohd Hassan, Norazian
Che Mohd Ramli, Neni Kartini
author_sort Mat So'ad, Siti Zaiton
building IIUM Repository
collection Online Access
description Entada spiralis Ridl. which is locally known as Sintok or Beluru is a woody climber with a characteristic spiral stem. The stem bark is traditionally used as natural shampoo and body wash among Malays due to its high content of saponins and its medicinal properties. The methanol extract of the stem bark possess promising antimicrobial activity against some species of skin diseases caused microbes The extract was further fractionation with different solvent gradient and repeated test on dermatophytes were done. The most active fraction is chloroform: methanol(9:1(V/V)). From this fraction we managed to isolate five compounds. The structure elucidation of the compounds were based on spectroscopic data ( 1H and 13C NMR, HMQC, HMBC and DEPT135).
first_indexed 2025-11-14T14:38:04Z
format Proceeding Paper
id iium-8023
institution International Islamic University Malaysia
institution_category Local University
language English
last_indexed 2025-11-14T14:38:04Z
publishDate 2011
recordtype eprints
repository_type Digital Repository
spelling iium-80232022-12-09T02:53:21Z http://irep.iium.edu.my/8023/ Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl Mat So'ad, Siti Zaiton Harun, Aiza Mohd Hassan, Norazian Che Mohd Ramli, Neni Kartini RS Pharmacy and materia medica Entada spiralis Ridl. which is locally known as Sintok or Beluru is a woody climber with a characteristic spiral stem. The stem bark is traditionally used as natural shampoo and body wash among Malays due to its high content of saponins and its medicinal properties. The methanol extract of the stem bark possess promising antimicrobial activity against some species of skin diseases caused microbes The extract was further fractionation with different solvent gradient and repeated test on dermatophytes were done. The most active fraction is chloroform: methanol(9:1(V/V)). From this fraction we managed to isolate five compounds. The structure elucidation of the compounds were based on spectroscopic data ( 1H and 13C NMR, HMQC, HMBC and DEPT135). 2011 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/8023/4/iirie2011.pdf Mat So'ad, Siti Zaiton and Harun, Aiza and Mohd Hassan, Norazian and Che Mohd Ramli, Neni Kartini (2011) Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl. In: IIUM Research, Invention and Innovation Exhibition (IRIIE) 2011, 9-10 February 2011, Cultural Activity Centre (CAC) and KAED Gallery IIUM. http://www.iium.edu.my/irie/11/
spellingShingle RS Pharmacy and materia medica
Mat So'ad, Siti Zaiton
Harun, Aiza
Mohd Hassan, Norazian
Che Mohd Ramli, Neni Kartini
Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl
title Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl
title_full Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl
title_fullStr Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl
title_full_unstemmed Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl
title_short Isolation of the compounds from antimicrobial active fraction from the stem barks of Entada spiralis Ridl
title_sort isolation of the compounds from antimicrobial active fraction from the stem barks of entada spiralis ridl
topic RS Pharmacy and materia medica
url http://irep.iium.edu.my/8023/
http://irep.iium.edu.my/8023/
http://irep.iium.edu.my/8023/4/iirie2011.pdf