Phytochemical screening and antioxidant activity of Psidium guajava

Psidium guajava or commonly known as guava is useful to treat gastroenteritis, dysentery, stomach pain and indigestion. In this study, the leaves of this species were screened for its phytochemical and antioxidant activity. The phytochemicals were extracted by sequential maceration by using n-hexane...

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Main Authors: Jani, Nor Akmalazura, Ahmad Azizi, Nurul Alia, Aminudin, Nurul Iman
Format: Article
Language:English
English
Published: Malaysian Analytical Sciences Society (ANALIS) 2020
Subjects:
Online Access:http://irep.iium.edu.my/80030/
http://irep.iium.edu.my/80030/1/11%29%20MJAS%20-%20PHYTOCHEMICAL%20SCREENING%20AND%20ANTIOXIDANT%20ACTIVITY%20OF%20Psidium%20guajava.pdf
http://irep.iium.edu.my/80030/3/80030_Phytochemical%20screening%20and%20antioxidant%20activity%20of%20psidium%20guajava_Scopus.pdf
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author Jani, Nor Akmalazura
Ahmad Azizi, Nurul Alia
Aminudin, Nurul Iman
author_facet Jani, Nor Akmalazura
Ahmad Azizi, Nurul Alia
Aminudin, Nurul Iman
author_sort Jani, Nor Akmalazura
building IIUM Repository
collection Online Access
description Psidium guajava or commonly known as guava is useful to treat gastroenteritis, dysentery, stomach pain and indigestion. In this study, the leaves of this species were screened for its phytochemical and antioxidant activity. The phytochemicals were extracted by sequential maceration by using n-hexane, chloroform and methanol, while phytochemical screening was performed using various chemical tests. Meanwhile, its antioxidant activity was assessed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Steroids and terpenoids were found to be present in the n-hexane extract, while phenols and terpenoids were detected in the chloroform extract. The methanol extract contained flavonoids, steroids, saponins, phenols and terpenoids. Among the tested extracts, the methanolic extract demonstrated strong DPPH radical scavenging activity with an IC50 value of 45.52 μg/mL.\ ******************************************************************************************************************************************** Psidium guajava atau dikenali sebagai jambu batu berguna bagi mengubati gastroenteritis, disenteri, sakit perut dan masalah pencernaan. Dalam kajian ini, daun spesis ini telah disaring untuk fitokimia dan aktiviti antioksidan. Fitokimia telah diekstrak menggunakan rendaman berturutan menggunakan n-heksana, kloroform dan metanol, manakala saringan fitokimia telah dijalankan menggunakan pelbagai ujian kimia. Sementara itu, aktiviti antioksidan telah dinilai menggunakan kaedah 2,2-difenil1-pikrilhidrazil (DPPH). Steroid and terpenoid telah didapati hadir di dalam ekstrak n-heksana, manakala fenol dan terpenoid telah dikesan di dalam ekstrak kloroform. Ekstrak metanol telah mengandungi flavonoid, steroid, saponin, fenol dan terpenoid. Di kalangan ekstrak yang diuji, ekstrak metanol menunjukkan aktiviti perencatan radikal DPPH yang kuat dengan nilai IC50 45.52 μg/mL.
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spelling iium-800302020-11-18T16:33:13Z http://irep.iium.edu.my/80030/ Phytochemical screening and antioxidant activity of Psidium guajava Jani, Nor Akmalazura Ahmad Azizi, Nurul Alia Aminudin, Nurul Iman QD Chemistry Psidium guajava or commonly known as guava is useful to treat gastroenteritis, dysentery, stomach pain and indigestion. In this study, the leaves of this species were screened for its phytochemical and antioxidant activity. The phytochemicals were extracted by sequential maceration by using n-hexane, chloroform and methanol, while phytochemical screening was performed using various chemical tests. Meanwhile, its antioxidant activity was assessed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Steroids and terpenoids were found to be present in the n-hexane extract, while phenols and terpenoids were detected in the chloroform extract. The methanol extract contained flavonoids, steroids, saponins, phenols and terpenoids. Among the tested extracts, the methanolic extract demonstrated strong DPPH radical scavenging activity with an IC50 value of 45.52 μg/mL.\ ******************************************************************************************************************************************** Psidium guajava atau dikenali sebagai jambu batu berguna bagi mengubati gastroenteritis, disenteri, sakit perut dan masalah pencernaan. Dalam kajian ini, daun spesis ini telah disaring untuk fitokimia dan aktiviti antioksidan. Fitokimia telah diekstrak menggunakan rendaman berturutan menggunakan n-heksana, kloroform dan metanol, manakala saringan fitokimia telah dijalankan menggunakan pelbagai ujian kimia. Sementara itu, aktiviti antioksidan telah dinilai menggunakan kaedah 2,2-difenil1-pikrilhidrazil (DPPH). Steroid and terpenoid telah didapati hadir di dalam ekstrak n-heksana, manakala fenol dan terpenoid telah dikesan di dalam ekstrak kloroform. Ekstrak metanol telah mengandungi flavonoid, steroid, saponin, fenol dan terpenoid. Di kalangan ekstrak yang diuji, ekstrak metanol menunjukkan aktiviti perencatan radikal DPPH yang kuat dengan nilai IC50 45.52 μg/mL. Malaysian Analytical Sciences Society (ANALIS) 2020-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/80030/1/11%29%20MJAS%20-%20PHYTOCHEMICAL%20SCREENING%20AND%20ANTIOXIDANT%20ACTIVITY%20OF%20Psidium%20guajava.pdf application/pdf en http://irep.iium.edu.my/80030/3/80030_Phytochemical%20screening%20and%20antioxidant%20activity%20of%20psidium%20guajava_Scopus.pdf Jani, Nor Akmalazura and Ahmad Azizi, Nurul Alia and Aminudin, Nurul Iman (2020) Phytochemical screening and antioxidant activity of Psidium guajava. Malaysian Journal of Analytical Sciences (MJAS), 24 (2). pp. 173-178. ISSN 1394-2506 https://mjas.analis.com.my/mjas/v24_n2/pdf/Akmalazura_24_2_3.pdf
spellingShingle QD Chemistry
Jani, Nor Akmalazura
Ahmad Azizi, Nurul Alia
Aminudin, Nurul Iman
Phytochemical screening and antioxidant activity of Psidium guajava
title Phytochemical screening and antioxidant activity of Psidium guajava
title_full Phytochemical screening and antioxidant activity of Psidium guajava
title_fullStr Phytochemical screening and antioxidant activity of Psidium guajava
title_full_unstemmed Phytochemical screening and antioxidant activity of Psidium guajava
title_short Phytochemical screening and antioxidant activity of Psidium guajava
title_sort phytochemical screening and antioxidant activity of psidium guajava
topic QD Chemistry
url http://irep.iium.edu.my/80030/
http://irep.iium.edu.my/80030/
http://irep.iium.edu.my/80030/1/11%29%20MJAS%20-%20PHYTOCHEMICAL%20SCREENING%20AND%20ANTIOXIDANT%20ACTIVITY%20OF%20Psidium%20guajava.pdf
http://irep.iium.edu.my/80030/3/80030_Phytochemical%20screening%20and%20antioxidant%20activity%20of%20psidium%20guajava_Scopus.pdf