Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone
Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still have no quantitative method to pr...
| Main Authors: | , , , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
Institute of Physics Publishing
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/79698/ http://irep.iium.edu.my/79698/1/79698_Biomechanical%20analysis%20of%20patient-specific%20femur%20_conf.%20article.pdf http://irep.iium.edu.my/79698/2/79698_Biomechanical%20analysis%20of%20patient-specific%20femur%20_scopus.pdf |
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| author | Tan, L. C. Mat Som, Mohd Hanafi Basarudin, Khairul Salleh Yazid, Haniza Daud, Ruslizam Awang, Mohamed Saufi |
| author_facet | Tan, L. C. Mat Som, Mohd Hanafi Basarudin, Khairul Salleh Yazid, Haniza Daud, Ruslizam Awang, Mohamed Saufi |
| author_sort | Tan, L. C. |
| building | IIUM Repository |
| collection | Online Access |
| description | Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy
fractures. The femur consists of cortical and cancellous bone, each with different mechanical
properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still
have no quantitative method to predict fractures. This project’s purpose is to investigate the
mechanical behaviour of patient-specific OI femur from the finite element analysis. The
fracture risk in daily activities (ADL) were examined. All the stress values were judged by the
fracture criteria, assumed as 115 MPa. The exercises that exerted force more than 6 times of
body weight could cause fractures. Cancellous bone was not affected in any case of ADL. The
effects of force and stress on cancellous bone and its impact on fracture risk are negligible. |
| first_indexed | 2025-11-14T17:46:54Z |
| format | Proceeding Paper |
| id | iium-79698 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:46:54Z |
| publishDate | 2019 |
| publisher | Institute of Physics Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-796982020-07-13T01:15:53Z http://irep.iium.edu.my/79698/ Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone Tan, L. C. Mat Som, Mohd Hanafi Basarudin, Khairul Salleh Yazid, Haniza Daud, Ruslizam Awang, Mohamed Saufi R Medicine (General) RD Surgery Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still have no quantitative method to predict fractures. This project’s purpose is to investigate the mechanical behaviour of patient-specific OI femur from the finite element analysis. The fracture risk in daily activities (ADL) were examined. All the stress values were judged by the fracture criteria, assumed as 115 MPa. The exercises that exerted force more than 6 times of body weight could cause fractures. Cancellous bone was not affected in any case of ADL. The effects of force and stress on cancellous bone and its impact on fracture risk are negligible. Institute of Physics Publishing 2019-12 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/79698/1/79698_Biomechanical%20analysis%20of%20patient-specific%20femur%20_conf.%20article.pdf application/pdf en http://irep.iium.edu.my/79698/2/79698_Biomechanical%20analysis%20of%20patient-specific%20femur%20_scopus.pdf Tan, L. C. and Mat Som, Mohd Hanafi and Basarudin, Khairul Salleh and Yazid, Haniza and Daud, Ruslizam and Awang, Mohamed Saufi (2019) Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone. In: "6th International Conference on Applications and Design in Mechanical Engineering 2019, ICADME 2019", 26 - 27 August 2019, Penang. https://iopscience.iop.org/article/10.1088/1757-899X/670/1/012045/pdf 10.1088/1757-899X/670/1/012045 |
| spellingShingle | R Medicine (General) RD Surgery Tan, L. C. Mat Som, Mohd Hanafi Basarudin, Khairul Salleh Yazid, Haniza Daud, Ruslizam Awang, Mohamed Saufi Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| title | Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| title_full | Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| title_fullStr | Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| title_full_unstemmed | Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| title_short | Biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| title_sort | biomechanical analysis of patient-specific femur model of osteogenesis imperfecta with cortical and cancellous bone |
| topic | R Medicine (General) RD Surgery |
| url | http://irep.iium.edu.my/79698/ http://irep.iium.edu.my/79698/ http://irep.iium.edu.my/79698/ http://irep.iium.edu.my/79698/1/79698_Biomechanical%20analysis%20of%20patient-specific%20femur%20_conf.%20article.pdf http://irep.iium.edu.my/79698/2/79698_Biomechanical%20analysis%20of%20patient-specific%20femur%20_scopus.pdf |