Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction
This study aims to predict the fracture of bone with osteogenesis imperfecta (OI) by considering the homogenization properties of real patient. A Type-III of osteotomy in OI femur was used as bone specimen. Nine representative volume element (RVE) models were developed based on μCT-images of bone...
| Main Authors: | , , , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
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Institute of Physics Publishing
2019
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| Online Access: | http://irep.iium.edu.my/79664/ http://irep.iium.edu.my/79664/1/79664_Fracture%20prediction%20on%20patient-specific_conf.%20article.pdf http://irep.iium.edu.my/79664/2/79664_Fracture%20prediction%20on%20patient-specific_scopus.pdf |
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| author | Mok, C J Basaruddin, Khairul Salleh Mat Som, Mohd Hanafi A. Majid, M.S.A. Sulaiman, Abdul Razak Awang, Mohd Shukrimi |
| author_facet | Mok, C J Basaruddin, Khairul Salleh Mat Som, Mohd Hanafi A. Majid, M.S.A. Sulaiman, Abdul Razak Awang, Mohd Shukrimi |
| author_sort | Mok, C J |
| building | IIUM Repository |
| collection | Online Access |
| description | This study aims to predict the fracture of bone with osteogenesis imperfecta (OI) by
considering the homogenization properties of real patient. A Type-III of osteotomy in OI femur
was used as bone specimen. Nine representative volume element (RVE) models were
developed based on μCT-images of bone specimen. Homogenized properties particularly the
Young's moduli of the RVEs was obtained based on homogenization theory in Voxelcon
software. The obtained homogenized properties were then assigned to the OI patient-specific
model that was developed from CT-images of real patient. The fracture of OI bone was
predicted based on linear static analysis and finite element method under loadings of activity
daily living (ADL). The results found that the fracture might be happen to the patient under
jumping load case, whereas the subject is expected to be safe under standing still and walking
load case. |
| first_indexed | 2025-11-14T17:46:47Z |
| format | Proceeding Paper |
| id | iium-79664 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:46:47Z |
| publishDate | 2019 |
| publisher | Institute of Physics Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-796642021-02-01T00:47:18Z http://irep.iium.edu.my/79664/ Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction Mok, C J Basaruddin, Khairul Salleh Mat Som, Mohd Hanafi A. Majid, M.S.A. Sulaiman, Abdul Razak Awang, Mohd Shukrimi R Medicine (General) RD701 Orthopedics TJ Mechanical engineering and machinery This study aims to predict the fracture of bone with osteogenesis imperfecta (OI) by considering the homogenization properties of real patient. A Type-III of osteotomy in OI femur was used as bone specimen. Nine representative volume element (RVE) models were developed based on μCT-images of bone specimen. Homogenized properties particularly the Young's moduli of the RVEs was obtained based on homogenization theory in Voxelcon software. The obtained homogenized properties were then assigned to the OI patient-specific model that was developed from CT-images of real patient. The fracture of OI bone was predicted based on linear static analysis and finite element method under loadings of activity daily living (ADL). The results found that the fracture might be happen to the patient under jumping load case, whereas the subject is expected to be safe under standing still and walking load case. Institute of Physics Publishing 2019-12-02 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/79664/1/79664_Fracture%20prediction%20on%20patient-specific_conf.%20article.pdf application/pdf en http://irep.iium.edu.my/79664/2/79664_Fracture%20prediction%20on%20patient-specific_scopus.pdf Mok, C J and Basaruddin, Khairul Salleh and Mat Som, Mohd Hanafi and A. Majid, M.S.A. and Sulaiman, Abdul Razak and Awang, Mohd Shukrimi (2019) Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction. In: "6th International Conference on Applications and Design in Mechanical Engineering 2019, ICADME 2019", 26 - 27 August 2019, Penang. https://iopscience.iop.org/article/10.1088/1757-899X/670/1/012073/meta 10.1088/1757-899X/670/1/012073 |
| spellingShingle | R Medicine (General) RD701 Orthopedics TJ Mechanical engineering and machinery Mok, C J Basaruddin, Khairul Salleh Mat Som, Mohd Hanafi A. Majid, M.S.A. Sulaiman, Abdul Razak Awang, Mohd Shukrimi Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction |
| title | Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction |
| title_full | Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction |
| title_fullStr | Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction |
| title_full_unstemmed | Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction |
| title_short | Fracture prediction on patient-specific tibia model with osteogenesis Imperfecta under various loading direction |
| title_sort | fracture prediction on patient-specific tibia model with osteogenesis imperfecta under various loading direction |
| topic | R Medicine (General) RD701 Orthopedics TJ Mechanical engineering and machinery |
| url | http://irep.iium.edu.my/79664/ http://irep.iium.edu.my/79664/ http://irep.iium.edu.my/79664/ http://irep.iium.edu.my/79664/1/79664_Fracture%20prediction%20on%20patient-specific_conf.%20article.pdf http://irep.iium.edu.my/79664/2/79664_Fracture%20prediction%20on%20patient-specific_scopus.pdf |