Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
Introduction: The mNUTRIC score is a nutritional assessment tool to identify critically ill patients with high nutritional risk who could benefit from nutritional interventions. This study was conducted to validate the 28-day mortality prognostic performance of the mNUTRIC score in a Malaysian inten...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
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Malaysian Journal of Nutrition
2019
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| Online Access: | http://irep.iium.edu.my/79023/ http://irep.iium.edu.my/79023/1/Vol%2025%283%29%207.mjn.2019.0074_Basri.pdf http://irep.iium.edu.my/79023/7/79023_Validation%20of%20the%2028-day%20mortality_scopus.pdf |
| _version_ | 1848788706265137152 |
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| author | Wan Muhd Shukeri, Wan Fadzlina Saeed, Samiullah Md Ralib, Azrina Mat Nor, Mohd Basri |
| author_facet | Wan Muhd Shukeri, Wan Fadzlina Saeed, Samiullah Md Ralib, Azrina Mat Nor, Mohd Basri |
| author_sort | Wan Muhd Shukeri, Wan Fadzlina |
| building | IIUM Repository |
| collection | Online Access |
| description | Introduction: The mNUTRIC score is a nutritional assessment tool to identify critically ill patients with high nutritional risk who could benefit from nutritional interventions. This study was conducted to validate the 28-day mortality prognostic performance of the mNUTRIC score in a Malaysian intensive care unit (ICU).
Methods: This was a retrospective cohort study of adult patients who were consecutively admitted to the ICU from January 2017 to December 2018 for >24 hours. Data were collected on variables required to calculate the mNUTRIC score. Patients with mNUTRIC score ≥5 points were considered to be at high nutritional risk. Main outcome was 28- day mortality from all causes; ICU length of stay (LOS) and prolonged mechanical ventilation (MV) (>2 days) were secondary outcomes.
Results: From a total of 432 admissions, 382 (88.4%) patients fulfilled the study criteria. Seventy-seven (20.2%) of these patients were at high nutritional risk. They had longer mean ICU LOS (7.1±7.5 days versus 4.2±4.0 days, p=0.001), greater proportion of prolonged MV (57.1% versus 14.4%, p<0.001) and higher 28-day mortality (44.2% versus 10.2%, p<0.001) compared to patients with low mNUTRIC score (≤4 points). High mNUTRIC score predicted 28-day mortality with area under the curve (AUC) of 0.797 (95% confidence interval: 0.738-0.856).
Conclusion: High mNUTRIC score was associated with a higher 28-day mortality. The prognostic performance for 28-day mortality of the mNUTRIC score is clinically valid as indicated by AUC >0.7 and is comparable to the results of other validation studies. In addition, patients with high mNUTRIC score had increased ICU LOS and prolonged MV.
Key words: Nutritional status, critically ill, mortality |
| first_indexed | 2025-11-14T17:45:05Z |
| format | Article |
| id | iium-79023 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:45:05Z |
| publishDate | 2019 |
| publisher | Malaysian Journal of Nutrition |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-790232020-03-18T01:46:04Z http://irep.iium.edu.my/79023/ Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit Wan Muhd Shukeri, Wan Fadzlina Saeed, Samiullah Md Ralib, Azrina Mat Nor, Mohd Basri RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid Introduction: The mNUTRIC score is a nutritional assessment tool to identify critically ill patients with high nutritional risk who could benefit from nutritional interventions. This study was conducted to validate the 28-day mortality prognostic performance of the mNUTRIC score in a Malaysian intensive care unit (ICU). Methods: This was a retrospective cohort study of adult patients who were consecutively admitted to the ICU from January 2017 to December 2018 for >24 hours. Data were collected on variables required to calculate the mNUTRIC score. Patients with mNUTRIC score ≥5 points were considered to be at high nutritional risk. Main outcome was 28- day mortality from all causes; ICU length of stay (LOS) and prolonged mechanical ventilation (MV) (>2 days) were secondary outcomes. Results: From a total of 432 admissions, 382 (88.4%) patients fulfilled the study criteria. Seventy-seven (20.2%) of these patients were at high nutritional risk. They had longer mean ICU LOS (7.1±7.5 days versus 4.2±4.0 days, p=0.001), greater proportion of prolonged MV (57.1% versus 14.4%, p<0.001) and higher 28-day mortality (44.2% versus 10.2%, p<0.001) compared to patients with low mNUTRIC score (≤4 points). High mNUTRIC score predicted 28-day mortality with area under the curve (AUC) of 0.797 (95% confidence interval: 0.738-0.856). Conclusion: High mNUTRIC score was associated with a higher 28-day mortality. The prognostic performance for 28-day mortality of the mNUTRIC score is clinically valid as indicated by AUC >0.7 and is comparable to the results of other validation studies. In addition, patients with high mNUTRIC score had increased ICU LOS and prolonged MV. Key words: Nutritional status, critically ill, mortality Malaysian Journal of Nutrition 2019-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/79023/1/Vol%2025%283%29%207.mjn.2019.0074_Basri.pdf application/pdf en http://irep.iium.edu.my/79023/7/79023_Validation%20of%20the%2028-day%20mortality_scopus.pdf Wan Muhd Shukeri, Wan Fadzlina and Saeed, Samiullah and Md Ralib, Azrina and Mat Nor, Mohd Basri (2019) Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit. Malaysian Journal of Nutrition, 25 (3). pp. 413-421. ISSN 1394-035X http://nutriweb.org.my/mjn/publication/25-3/Vol%2025(3)%207.mjn.2019.0074%20Wan%20Fadzlina_final%20(online%20first).pdf 10.31246/mjn-2019-0074 |
| spellingShingle | RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid Wan Muhd Shukeri, Wan Fadzlina Saeed, Samiullah Md Ralib, Azrina Mat Nor, Mohd Basri Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit |
| title | Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit |
| title_full | Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit |
| title_fullStr | Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit |
| title_full_unstemmed | Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit |
| title_short | Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit |
| title_sort | validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a malaysian intensive care unit |
| topic | RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid |
| url | http://irep.iium.edu.my/79023/ http://irep.iium.edu.my/79023/ http://irep.iium.edu.my/79023/ http://irep.iium.edu.my/79023/1/Vol%2025%283%29%207.mjn.2019.0074_Basri.pdf http://irep.iium.edu.my/79023/7/79023_Validation%20of%20the%2028-day%20mortality_scopus.pdf |