CARP-1 functional mimetics: a novel class of small molecule inhibitors of cancer cell growth and metastasis
CARP-1/CCAR1 is a peri-nuclear phospho-protein which functions as a co-activator of the cell cycle regulatory anaphase promoting complex/cyclosome (APC/C) E3 ligase. CARP-1 functional mimetics (CFMs) are a class of small molecule compounds that inhibit CARP-1 binding with APC/C subunit APC-2. CFM-4,...
| Main Author: | Ashour, Abdelkader Elbadawy Abbas |
|---|---|
| Format: | Proceeding Paper |
| Language: | English English English |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/78960/ http://irep.iium.edu.my/78960/1/Dr.%20Abdelkader%20Ashour%20Keynote%20Speaker.pdf http://irep.iium.edu.my/78960/2/Pharmacology%202019_Book%20Final.pdf http://irep.iium.edu.my/78960/13/CARP-1%20functional%20mimetics%20A%20novel%20class%20of%20small%20molecule%20inhibitors%20of%20cancer%20cell%20growth%20and%20metastasis%20F.pdf |
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