Investigation of α‐glucosidase inhibitory metabolites from Tetracera scandens leaves by GC–MS metabolite profiling and docking studies

QR Code

Investigation of α‐glucosidase inhibitory metabolites from Tetracera scandens leaves by GC–MS metabolite profiling and docking studies

Abstract: Stone leaf (Tetracera scandens) is a Southeast Asian medicinal plant that has been traditionally used for the management of diabetes mellitus. The underlying mechanisms of the antidiabetic activity have not been fully explored yet. Hence, this study aime...

Full description

Bibliographic Details
Main Authors:	Ahmed, Nokhala, Siddiqui, Mohammad Jamshed Ahmad, Ahmed, Qamar Uddin, Ahamad Bustamam, Muhammad Safwan, Zakaria, Zainul Amiruddin
Format:	Article
Language:	English English
Published:	Multidisciplinary Digital Publishing Institute (MDPI) 2020
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/78713/ http://irep.iium.edu.my/78713/7/78713_Investigation%20%20of%20%20%CE%B1%E2%80%90glucosidase%20%20inhibitory%20%20metabolites%20from%20%20Tetracera%20%28Scopus%29.pdf http://irep.iium.edu.my/78713/13/78713_Investigation%20%20of%20%20%CE%B1%E2%80%90glucosidase%20%20inhibitory%20%20metabolites.pdf

Similar Items

Investigation of α-glucosidase inhibitory metabolites from Tetracera scandens leaves by GC–MS metabolite profiling and docking studies
by: Nokhala, Ahmed, et al.
Published: (2020)

Phytochemicals and biological activity of Tetracera scandens Linn. Merr. (Dilleniaceae): a short review
by: Nokhala, Ahmed, et al.
Published: (2020)

GC-MS-Based metabolite profiling of cosmos caudatus leaves possessing alpha-glucosidase inhibitory activity
by: Javadi, Neda, et al.
Published: (2014)

GC-MS-based metabolite profiling of Cosmos caudatus leaves possessing alpha-glucosidase inhibitory activity
by: Javadi, Neda, et al.
Published: (2014)

GC-MS-based metabolites profiling of Cosmos caudatus kunth leaves possessing alpha-glucosidase inhibitory activity
by: Javadi, Neda
Published: (2014)

Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages
by: Wan Ahmad, Wan Nadilah, et al.
Published: (2019)

Variation in the metabolites and αglucosidase inhibitory activity of Cosmos caudatus at different growth stages
by: Wan Ahmad, Wan Nadilah, et al.
Published: (2019)

Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages
by: Wan Ahmad, Wan Nadilah Adibah, et al.
Published: (2019)

GC-MS analysis of metabolites from soxhlet extraction, ultrasound-assisted extraction and supercritical fluid extraction of Salacca zalacca flesh and its alpha-glucosidase inhibitory activity
by: Saleh, Mohammed S M, et al.
Published: (2019)

In vitro α- glucosidase inhibitory and antioxidant activities of extract, fractions and isolated compounds from Tetracera macrophylla vall leaf
by: Opeyemi Roheem, Fatimah, et al.
Published: (2017)

Potentially bioactive metabolites from pineapple waste extracts and their antioxidant and α-glucosidase inhibitory activities by 1H NMR
by: Azizan, Awanis, et al.
Published: (2020)

Insilico and invitro investigations of alpha-glucosidase inhibitory activity of phenolic constituents of tetracera indica
by: Muhammad Alhassan, Alhassan, et al.
Published: (2017)

α-Glucosidase inhibitory activity of selected Malaysian plants
by: Mohd Bukhari, Dzatil Awanis, et al.
Published: (2017)

In vitro antioxidant and, α-glucosidase inhibitory activities and comprehensive metabolite profiling of methanol extract and its fractions from Clinacanthus nutans
by: Alam, Md. Ariful, et al.
Published: (2017)

Metabolite profiling of Neptunia oleracea and correlation with antioxidant and α-glucosidase inhibitory activities using 1H NMR-based metabolomics
by: Lee, Soo Yee, et al.
Published: (2016)

Metabolite profiling of Neptunia oleracea and correlation with antioxidant and α-glucosidase inhibitory activities using 1H NMR-based metabolomics
by: Lee, Soo Yee, et al.
Published: (2016)

Phytochemical investigation of the leaves of tetracera scandens Linn and in vitro antidiabetic activity of hypoletin
by: Ahmed, Qamar Uddin, et al.
Published: (2014)

α-Glucosidase inhibitors: consistency of: in silico docking data with in vitro inhibitory data and inhibitory effect prediction of quercetin derivatives
by: Zhu, Jianzhong, et al.
Published: (2019)

Antidiabetic activity of the methanol extract of the leaves of Tetracera scandens Linn., in alloxan induced diabetic rats
by: Umar, Abdulrashid, et al.
Published: (2009)

A new sulphated flavone and other phytoconstituents from the leaves of Tetracera indica Merr. and their alpha-glucosidase inhibitory activity
by: Alhassan, Alhassan Muhammad, et al.
Published: (2019)

Anti-hyperglecemic activity of the leaves of Tetracera scandens Linn. (Dilleniaveae) in alloxan induced diabetic male albino wistar rats
by: Ahmed, Qamar Uddin, et al.
Published: (2010)

Anti-hyperglycaemic activity of the leaves of Tetracera Scandens Linn (dilleniaceae) in Alloxan induced diabetic male albino wistar rats
by: Ahmed, Qamar Uddin, et al.
Published: (2010)

Sulfate-reducing bacteria metabolite detection using GC-MS
by: Nawawi, M.F., et al.
Published: (2014)

Correlation between metabolite profile and phytochemical characteristics of Ipomoea aquatica Forssk. with its antioxidant and α-glucosidase inhibitory activities using NMR-based metabolomics
by: Lawal, Umar
Published: (2016)

Antioxidant, α-glucosidase and nitric oxide inhibitory activities of Phyllanthus acidus L. leaves in correlation with their metabolites using ¹H-NMR- and LCMS-based metabolomics
by: Abd Ghafar, Siti Zulaikha
Published: (2019)

Antioxidants and α-glucosidase inhibitory activities from peels of Salak (Salacca zalacca) fruit
by: Saleh, Mohammed S M, et al.
Published: (2017)

Metabolite profiling and characterization of Lupinus albus L. and its correlation with antioxidant and alpha-glucosidase inhibitory activities
by: Khaoula, Hellal
Published: (2021)

Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study
by: Pramai, Phaiwan, et al.
Published: (2018)

Exploration of the antidiabetic potential of the leaves of Tetracera scandens Linn., (Mempelas Kesar) in alloxan induced diabetic wister rats
by: Ahmed, Qamar Uddin, et al.
Published: (2009)

Anti-hyperglycemic activity of the leaves of Tetracera scandens Linn. Merr. (Dilleniaceae) in alloxan induced diabetic rats
by: Umar, Abdulrashid, et al.
Published: (2010)

FT-IR- based metabolomics approach to characterize the α-glucosidase inhibitory activity of Salak fruit
by: Saleh, Mohammed S M, et al.
Published: (2017)

Effect of different drying treatments and different extraction methods on α-glucosidase inhibitory activities of S. zalacca fruit
by: Siddiqui, Mohammad Jamshed Ahmad, et al.
Published: (2019)

Isolation and structure elucidation of two new novel flavonoids and antidiabetic activity of the leaves of Tetracera scandens Linn. in vivo.
by: Umar, Abdulrashid, et al.
Published: (2011)

Synthesis of cinnamamide derivatives and their α-glucosidase inhibitory activities
by: Teni Ernawati,, et al.
Published: (2020)

Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves - GCMS based metabolomics approach
by: Javadi, Neda, et al.
Published: (2015)

α - Glucosidase inhibitory and antioxidant activities of entada spiralis ridl. (Sintok) stem bark extracts
by: Opeyemi Roheem, Fatimah, et al.
Published: (2019)

Identification of α-glucosidase inhibitory compounds from Curcuma mangga fractions
by: Awin, Tahani M., et al.
Published: (2020)

Correlation of the GC-MS-based metabolite profile of Momordica charantia fruit and its antioxidant activity
by: V., Perumal, et al.
Published: (2022)

Flavonoids from Cynometra cauliflora and their antioxidant, α-Glucosidase, and Cholinesterase inhibitory activities
by: Ado, Muhammad Abubakar, et al.
Published: (2019)

Rapid investigation of α-glucosidase inhibitory activity of Clinacanthus nutans leaf using infrared fingerprinting
by: Murugesu, Suganya, et al.
Published: (2019)