Synthesis, characterization and cytotoxic activity of S-benzyldithiocarbazate Schiff bases derived from 5-fluoroisatin, 5-chloroisatin, 5-bromoisatin and their crystal structures

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Synthesis, characterization and cytotoxic activity of S-benzyldithiocarbazate Schiff bases derived from 5-fluoroisatin, 5-chloroisatin, 5-bromoisatin and their crystal structures

Schiff bases were prepared from S-benzyldithiocarbazate with 5-fluro-, 5-chloro- and 5-bromoisatin. All are potential tridentate nitrogen, oxygen, sulfur donors. They were found to be selectively active against MCF-7 cell line (Human non-metastatic mammary gland adenocarcinoma cell line). The bro...

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Bibliographic Details
Main Authors:	Abdul Manan, Mohd Abdul Fatah, Crouse, Karen Anne, Mohamed Tahir, Mohamed Ibrahim, Rosli, Rozita, How, Fiona Ni Foong, Watkins, David J., Slawin, Alexandra Martha Zoya
Format:	Article
Language:	English
Published:	Springer New York LLC 2011
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/7866/ http://irep.iium.edu.my/7866/1/JOCC_41_1630-1641.pdf

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