Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia
Most of the decisions regarding diagnosis and treatment are based on laboratory test results. Urinary tract infections (UTIs) are among the most common infections in humans. The changing antimicrobial sensitivity in UTI requires appropriate antibiotics. Antimicrobial resistance is an emerging proble...
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Wolters Kluwer Medknow Publications
2019
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| Online Access: | http://irep.iium.edu.my/76119/ http://irep.iium.edu.my/76119/13/76119_Relationship%20between%20antimicrobial%20prescribing_article.pdf http://irep.iium.edu.my/76119/2/76119_Relationship%20between%20antimicrobial%20prescribing_SCOPUS.pdf http://irep.iium.edu.my/76119/14/76119_Relationship%20between%20antimicrobial%20prescribing_wos.pdf |
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| author | Alsohaim, Sulaiman I. A. Bawadikji, Abdulkader A. Bawadikji Elkalmi, Ramadan Elkalmi Mustafa Mahmoud, Mohammed Imad Al-Deen Hassali, Mohamed Azmi |
| author_facet | Alsohaim, Sulaiman I. A. Bawadikji, Abdulkader A. Bawadikji Elkalmi, Ramadan Elkalmi Mustafa Mahmoud, Mohammed Imad Al-Deen Hassali, Mohamed Azmi |
| author_sort | Alsohaim, Sulaiman I. A. |
| building | IIUM Repository |
| collection | Online Access |
| description | Most of the decisions regarding diagnosis and treatment are based on laboratory test results. Urinary tract infections (UTIs) are among the most common infections in humans. The changing antimicrobial sensitivity in UTI requires appropriate antibiotics. Antimicrobial resistance is an emerging problem in the Kingdom of Saudi Arabia where the complete reversal of antimicrobial resistance is difficult due to irrational use of antibiotics. Objectives: This study aimed to determine the most common bacterial agents causing UTI in different seasons among patients who were admitted to Buraidah Central Hospital (BCH), Saudi Arabia. The study also evaluated the link between prescribing and resistance toward antimicrobials. Materials and Methods: A 6-month retrospective study was conducted among adult patients who were admitted to the inpatient department at BCH. A total of 379 files were collected from microbiological laboratory for inpatients. Results: Most UTI-causing bacteria prevailed in the same season. Of 15 bacterial strains, 12 were significantly correlated with 20 (of a total of 40) antibiotics that were used. Most bacteria were gram-negative. Gram-negative bacilli including Escherichia coli, Klebsiella spp., and Pseudomonadaceae and gram-positive Enterococcus faecalis were most frequently causing UTIs. Conclusion: Overall prevalence of antibiotic resistance was negative in bacterial isolates. However, the relationship between antimicrobial prescribing and antimicrobial resistance was significantly negative among UTI patients in BCH, Saudi Arabia. |
| first_indexed | 2025-11-14T17:37:35Z |
| format | Article |
| id | iium-76119 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T17:37:35Z |
| publishDate | 2019 |
| publisher | Wolters Kluwer Medknow Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-761192019-12-10T03:55:49Z http://irep.iium.edu.my/76119/ Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia Alsohaim, Sulaiman I. A. Bawadikji, Abdulkader A. Bawadikji Elkalmi, Ramadan Elkalmi Mustafa Mahmoud, Mohammed Imad Al-Deen Hassali, Mohamed Azmi RM Therapeutics. Pharmacology Most of the decisions regarding diagnosis and treatment are based on laboratory test results. Urinary tract infections (UTIs) are among the most common infections in humans. The changing antimicrobial sensitivity in UTI requires appropriate antibiotics. Antimicrobial resistance is an emerging problem in the Kingdom of Saudi Arabia where the complete reversal of antimicrobial resistance is difficult due to irrational use of antibiotics. Objectives: This study aimed to determine the most common bacterial agents causing UTI in different seasons among patients who were admitted to Buraidah Central Hospital (BCH), Saudi Arabia. The study also evaluated the link between prescribing and resistance toward antimicrobials. Materials and Methods: A 6-month retrospective study was conducted among adult patients who were admitted to the inpatient department at BCH. A total of 379 files were collected from microbiological laboratory for inpatients. Results: Most UTI-causing bacteria prevailed in the same season. Of 15 bacterial strains, 12 were significantly correlated with 20 (of a total of 40) antibiotics that were used. Most bacteria were gram-negative. Gram-negative bacilli including Escherichia coli, Klebsiella spp., and Pseudomonadaceae and gram-positive Enterococcus faecalis were most frequently causing UTIs. Conclusion: Overall prevalence of antibiotic resistance was negative in bacterial isolates. However, the relationship between antimicrobial prescribing and antimicrobial resistance was significantly negative among UTI patients in BCH, Saudi Arabia. Wolters Kluwer Medknow Publications 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/76119/13/76119_Relationship%20between%20antimicrobial%20prescribing_article.pdf application/pdf en http://irep.iium.edu.my/76119/2/76119_Relationship%20between%20antimicrobial%20prescribing_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/76119/14/76119_Relationship%20between%20antimicrobial%20prescribing_wos.pdf Alsohaim, Sulaiman I. A. and Bawadikji, Abdulkader A. Bawadikji and Elkalmi, Ramadan Elkalmi and Mustafa Mahmoud, Mohammed Imad Al-Deen and Hassali, Mohamed Azmi (2019) Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia. Journal of Pharmacy and Bioallied Sciences, 11 (2). pp. 162-169. ISSN 09757406 http://www.jpbsonline.org/showBackIssue.asp?issn=0975-7406;year=2019;volume=11;issue=2;month=April-June 10.4103/JPBS.JPBS_217_18 |
| spellingShingle | RM Therapeutics. Pharmacology Alsohaim, Sulaiman I. A. Bawadikji, Abdulkader A. Bawadikji Elkalmi, Ramadan Elkalmi Mustafa Mahmoud, Mohammed Imad Al-Deen Hassali, Mohamed Azmi Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia |
| title | Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia |
| title_full | Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia |
| title_fullStr | Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia |
| title_full_unstemmed | Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia |
| title_short | Relationship between antimicrobial prescribing and antimicrobial resistance among UTI patients at Buraidah Central Hospital, Saudi Arabia |
| title_sort | relationship between antimicrobial prescribing and antimicrobial resistance among uti patients at buraidah central hospital, saudi arabia |
| topic | RM Therapeutics. Pharmacology |
| url | http://irep.iium.edu.my/76119/ http://irep.iium.edu.my/76119/ http://irep.iium.edu.my/76119/ http://irep.iium.edu.my/76119/13/76119_Relationship%20between%20antimicrobial%20prescribing_article.pdf http://irep.iium.edu.my/76119/2/76119_Relationship%20between%20antimicrobial%20prescribing_SCOPUS.pdf http://irep.iium.edu.my/76119/14/76119_Relationship%20between%20antimicrobial%20prescribing_wos.pdf |