Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
Introduction: Data from the US showed that there are increasing evidences of opioid-related harms such as opioid overdose deaths in long term opioid use for the treatment of chronic non-cancer pain. There is lack of data from Malaysia on opioid use particularly on its opioid related clinical outcom...
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| Format: | Proceeding Paper |
| Language: | English English English |
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2019
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| Online Access: | http://irep.iium.edu.my/76016/ http://irep.iium.edu.my/76016/1/191104_main%20page_program.pdf http://irep.iium.edu.my/76016/2/191104_asween_poster_program.pdf http://irep.iium.edu.my/76016/3/191105_ICPRP_poster_Asween.pdf |
| _version_ | 1848788220024717312 |
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| author | Abdullah Sani, Asween Rowena Zin, Che Suraya |
| author_facet | Abdullah Sani, Asween Rowena Zin, Che Suraya |
| author_sort | Abdullah Sani, Asween Rowena |
| building | IIUM Repository |
| collection | Online Access |
| description | Introduction: Data from the US showed that there are increasing evidences of opioid-related harms such as opioid overdose deaths in long term opioid use for the treatment of chronic non-cancer pain. There is lack of data from Malaysia on opioid use particularly on its opioid related clinical outcomes.
Objectives: To examine the clinical outcomes and quality of life of short-term and long-term opioid use in patients with non-cancer pain.
Methods: This was a prospective clinical study where patients (age ≥18 years old) with non-cancer pain currently treated with opioids were recruited from three pain clinics in Malaysia. Patients were stratified into short-term or long-term opioid users based on opioid use ≥ 90 days. Outcome measures included pain intensity and pain interference with daily activities assessed by Brief Pain Inventory-Short Form, health-related quality of life assessed by Short-Form 36v2 and pain medication profiles assessed by Medication Quantification Scale-III (MQS-III. These measures were compared between short- and long-term opioid users.
Results: Of the 61 non-cancer pain patients recruited, 49.2% (n=) were short-term and 50.8%(n=) were long-term opioid users. There were no statistically significant differences in the pain intensity, overall pain interference, health-related quality of life, and pain medication profiles between short-term and long-term opioid users in this study.
Conclusion: Long-term opioid use did not significantly improve the clinical outcomes of patients with non-cancer pain which further supports the evidence of lack of benefits of opioids therapy in this condition. |
| first_indexed | 2025-11-14T17:37:21Z |
| format | Proceeding Paper |
| id | iium-76016 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T17:37:21Z |
| publishDate | 2019 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-760162019-11-12T07:23:19Z http://irep.iium.edu.my/76016/ Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain Abdullah Sani, Asween Rowena Zin, Che Suraya RM Therapeutics. Pharmacology Introduction: Data from the US showed that there are increasing evidences of opioid-related harms such as opioid overdose deaths in long term opioid use for the treatment of chronic non-cancer pain. There is lack of data from Malaysia on opioid use particularly on its opioid related clinical outcomes. Objectives: To examine the clinical outcomes and quality of life of short-term and long-term opioid use in patients with non-cancer pain. Methods: This was a prospective clinical study where patients (age ≥18 years old) with non-cancer pain currently treated with opioids were recruited from three pain clinics in Malaysia. Patients were stratified into short-term or long-term opioid users based on opioid use ≥ 90 days. Outcome measures included pain intensity and pain interference with daily activities assessed by Brief Pain Inventory-Short Form, health-related quality of life assessed by Short-Form 36v2 and pain medication profiles assessed by Medication Quantification Scale-III (MQS-III. These measures were compared between short- and long-term opioid users. Results: Of the 61 non-cancer pain patients recruited, 49.2% (n=) were short-term and 50.8%(n=) were long-term opioid users. There were no statistically significant differences in the pain intensity, overall pain interference, health-related quality of life, and pain medication profiles between short-term and long-term opioid users in this study. Conclusion: Long-term opioid use did not significantly improve the clinical outcomes of patients with non-cancer pain which further supports the evidence of lack of benefits of opioids therapy in this condition. 2019-10-19 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/76016/1/191104_main%20page_program.pdf application/pdf en http://irep.iium.edu.my/76016/2/191104_asween_poster_program.pdf application/pdf en http://irep.iium.edu.my/76016/3/191105_ICPRP_poster_Asween.pdf Abdullah Sani, Asween Rowena and Zin, Che Suraya (2019) Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019), 19-20th October 2019, Hotel Istana Kuala Lumpur. (Unpublished) |
| spellingShingle | RM Therapeutics. Pharmacology Abdullah Sani, Asween Rowena Zin, Che Suraya Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| title | Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| title_full | Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| title_fullStr | Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| title_full_unstemmed | Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| title_short | Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| title_sort | clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain |
| topic | RM Therapeutics. Pharmacology |
| url | http://irep.iium.edu.my/76016/ http://irep.iium.edu.my/76016/1/191104_main%20page_program.pdf http://irep.iium.edu.my/76016/2/191104_asween_poster_program.pdf http://irep.iium.edu.my/76016/3/191105_ICPRP_poster_Asween.pdf |