Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease...
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| Format: | Article |
| Language: | English |
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Science Forecast Publications
2019
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| Online Access: | http://irep.iium.edu.my/74793/ http://irep.iium.edu.my/74793/1/Dr.%20Mohd%20Aug%20NPSLE.pdf |
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| author | Mohd Hanafi, Mohd Sharil Iman Che' Man, Mohamad Che Alhadi, Shahidah |
| author_facet | Mohd Hanafi, Mohd Sharil Iman Che' Man, Mohamad Che Alhadi, Shahidah |
| author_sort | Mohd Hanafi, Mohd Sharil Iman |
| building | IIUM Repository |
| collection | Online Access |
| description | Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease [1]. We highlighted a case of a man, lived with diagnosis of Schizophrenia for almost 15 years subsequently revealed him suffered from neuropsychiatric lupus as he fulfilled the SLE classification criteria. His initial presentation was altered sensorium treated as acute psychosis- the tip of an iceberg to the underlying disease [2]. His multiple admissions to psychiatric ward were believed contributed by episode of lupus flare [2,3]. Necessary investigation is important to exclude another medical condition before make a diagnosis of Schizophrenia using DSM-V criteria [2]. The misdiagnosis has significantly impaired his social life and untreated disease had leads to morbidity and severe organ damage. This case emphasizes on the crucial aspect of assessing patient as a whole, follow-up the progression and re-evaluates patient’s condition for a new hint. Even though there is no cure yet for SLE, correct and early diagnosis is able to guide for individualized treatment and thus helping in good disease control that warrant better outcome [4]. |
| first_indexed | 2025-11-14T17:34:06Z |
| format | Article |
| id | iium-74793 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T17:34:06Z |
| publishDate | 2019 |
| publisher | Science Forecast Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-747932022-05-10T02:47:02Z http://irep.iium.edu.my/74793/ Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report Mohd Hanafi, Mohd Sharil Iman Che' Man, Mohamad Che Alhadi, Shahidah R Medicine (General) RA Public aspects of medicine Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease [1]. We highlighted a case of a man, lived with diagnosis of Schizophrenia for almost 15 years subsequently revealed him suffered from neuropsychiatric lupus as he fulfilled the SLE classification criteria. His initial presentation was altered sensorium treated as acute psychosis- the tip of an iceberg to the underlying disease [2]. His multiple admissions to psychiatric ward were believed contributed by episode of lupus flare [2,3]. Necessary investigation is important to exclude another medical condition before make a diagnosis of Schizophrenia using DSM-V criteria [2]. The misdiagnosis has significantly impaired his social life and untreated disease had leads to morbidity and severe organ damage. This case emphasizes on the crucial aspect of assessing patient as a whole, follow-up the progression and re-evaluates patient’s condition for a new hint. Even though there is no cure yet for SLE, correct and early diagnosis is able to guide for individualized treatment and thus helping in good disease control that warrant better outcome [4]. Science Forecast Publications 2019-08-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74793/1/Dr.%20Mohd%20Aug%20NPSLE.pdf Mohd Hanafi, Mohd Sharil Iman and Che' Man, Mohamad and Che Alhadi, Shahidah (2019) Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report. Journal of Family Medicine Forecast, 2 (2). pp. 1-3. ISSN 2643-7864 https://scienceforecastoa.com/Articles/JFM-V2-E2-1021.pdf |
| spellingShingle | R Medicine (General) RA Public aspects of medicine Mohd Hanafi, Mohd Sharil Iman Che' Man, Mohamad Che Alhadi, Shahidah Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report |
| title | Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report |
| title_full | Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report |
| title_fullStr | Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report |
| title_full_unstemmed | Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report |
| title_short | Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report |
| title_sort | neuropsychiatric systemic lupus erythematosus (npsle) – masquerade diagnosis: a case report |
| topic | R Medicine (General) RA Public aspects of medicine |
| url | http://irep.iium.edu.my/74793/ http://irep.iium.edu.my/74793/ http://irep.iium.edu.my/74793/1/Dr.%20Mohd%20Aug%20NPSLE.pdf |