Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia

Blastocystis sp. is a common enteric protozoan parasite found in humans and various types of animals worldwide. Recently, genotypic distribution of Blastocystis sp. were revealed in insects, rodents, avian and mammals, which exposed its potential of transmiting the infection to human. However, very...

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Main Authors: Kamaruddin, Sitie Kasmadiana, Mohammad, Mardhiah, Mat Yusof, Afzan
Format: Article
Language:English
English
Published: Malaysian Society of Parasitology and Tropical Medicine (MSPTM) 2020
Subjects:
Online Access:http://irep.iium.edu.my/74331/
http://irep.iium.edu.my/74331/13/74331_Prevalence%20and%20subtype%20distribution%20of%20Blastocystis%20sp.%20in_Scopus.pdf
http://irep.iium.edu.my/74331/14/74331_Prevalence%20and%20subtype%20distribution%20of%20Blastocystis%20sp.%20in_Scopus.pdf
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author Kamaruddin, Sitie Kasmadiana
Mohammad, Mardhiah
Mat Yusof, Afzan
author_facet Kamaruddin, Sitie Kasmadiana
Mohammad, Mardhiah
Mat Yusof, Afzan
author_sort Kamaruddin, Sitie Kasmadiana
building IIUM Repository
collection Online Access
description Blastocystis sp. is a common enteric protozoan parasite found in humans and various types of animals worldwide. Recently, genotypic distribution of Blastocystis sp. were revealed in insects, rodents, avian and mammals, which exposed its potential of transmiting the infection to human. However, very little information on current levels of Blastocystis sp. infection were reported in cattle from Malaysia. Herein, a total of 120 stool samples of cattles were collected. While the potential risk of infection such as age, gender, body score, diarrheic condition of the cattle were noted, and the condition as well as the management of the farms was also recorded. All stool sample were cultured, but 80 samples were selected for PCR sequencing analysis. The cultivation and microscopic examination revealed only 25% of the cattle (30/120) were infected with Blastocystis sp.. But, 43.8% of the cattle (35/80) were found positive upon PCR sequencing. The study also found that age, body score condition, diarrheic condition and certain farm were associated with the infection (p<0.05). Six subtypes (STs) that were discovered during the study were ST10 (21.3%;17/35), ST5 (8.8%;7/35), ST3 (7.5%;6/35), ST1 (2.5%;2/35), ST4 (2.5%;2/35) and ST14 (1.3%;1/35). Thus, moderate infections and variants in the genotypic distributions of the cattle suggest its potential for zoonotic transmission. Therefore, this findings could be helpful for further understanding the parasite, which assist studies of its pathogenicity.
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spelling iium-743312020-11-11T07:01:52Z http://irep.iium.edu.my/74331/ Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia Kamaruddin, Sitie Kasmadiana Mohammad, Mardhiah Mat Yusof, Afzan Q Science (General) R Medicine (General) Blastocystis sp. is a common enteric protozoan parasite found in humans and various types of animals worldwide. Recently, genotypic distribution of Blastocystis sp. were revealed in insects, rodents, avian and mammals, which exposed its potential of transmiting the infection to human. However, very little information on current levels of Blastocystis sp. infection were reported in cattle from Malaysia. Herein, a total of 120 stool samples of cattles were collected. While the potential risk of infection such as age, gender, body score, diarrheic condition of the cattle were noted, and the condition as well as the management of the farms was also recorded. All stool sample were cultured, but 80 samples were selected for PCR sequencing analysis. The cultivation and microscopic examination revealed only 25% of the cattle (30/120) were infected with Blastocystis sp.. But, 43.8% of the cattle (35/80) were found positive upon PCR sequencing. The study also found that age, body score condition, diarrheic condition and certain farm were associated with the infection (p<0.05). Six subtypes (STs) that were discovered during the study were ST10 (21.3%;17/35), ST5 (8.8%;7/35), ST3 (7.5%;6/35), ST1 (2.5%;2/35), ST4 (2.5%;2/35) and ST14 (1.3%;1/35). Thus, moderate infections and variants in the genotypic distributions of the cattle suggest its potential for zoonotic transmission. Therefore, this findings could be helpful for further understanding the parasite, which assist studies of its pathogenicity. Malaysian Society of Parasitology and Tropical Medicine (MSPTM) 2020-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74331/13/74331_Prevalence%20and%20subtype%20distribution%20of%20Blastocystis%20sp.%20in_Scopus.pdf application/pdf en http://irep.iium.edu.my/74331/14/74331_Prevalence%20and%20subtype%20distribution%20of%20Blastocystis%20sp.%20in_Scopus.pdf Kamaruddin, Sitie Kasmadiana and Mohammad, Mardhiah and Mat Yusof, Afzan (2020) Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia. Tropical Biomedicine, 37 (1). pp. 127-141. ISSN 0127-5720 E-ISSN 2521-9855 http://msptm.org/files/Vol37No1/127-141-Mohammad-M.pdf
spellingShingle Q Science (General)
R Medicine (General)
Kamaruddin, Sitie Kasmadiana
Mohammad, Mardhiah
Mat Yusof, Afzan
Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia
title Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia
title_full Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia
title_fullStr Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia
title_full_unstemmed Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia
title_short Prevalence and subtype distribution of blastocystis sp. in cattle from Pahang, Malaysia
title_sort prevalence and subtype distribution of blastocystis sp. in cattle from pahang, malaysia
topic Q Science (General)
R Medicine (General)
url http://irep.iium.edu.my/74331/
http://irep.iium.edu.my/74331/
http://irep.iium.edu.my/74331/13/74331_Prevalence%20and%20subtype%20distribution%20of%20Blastocystis%20sp.%20in_Scopus.pdf
http://irep.iium.edu.my/74331/14/74331_Prevalence%20and%20subtype%20distribution%20of%20Blastocystis%20sp.%20in_Scopus.pdf