Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
Introduction: Hypertension is the most prevalent risk factor of cardiovascular diseases in Malaysia. 17.3% of hypertension cases in Malaysia is attributed to adults aged 18 to 39 years. Psychosocial distress is a possible risk factor for elevated blood pressure in young adults, and cortisol could be...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Proceeding Paper |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/73872/ http://irep.iium.edu.my/73872/19/Psychosocial%20Distress%20and%20Blood%20Pressure%20among%20Young%20Adults.pdf |
| _version_ | 1848787873625538560 |
|---|---|
| author | Wan Omar, Wan Fatein Nabeila Musa, Ramli Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah A.Talib, Norlelawati Aung, Sithu Abdullah, Aszrin |
| author_facet | Wan Omar, Wan Fatein Nabeila Musa, Ramli Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah A.Talib, Norlelawati Aung, Sithu Abdullah, Aszrin |
| author_sort | Wan Omar, Wan Fatein Nabeila |
| building | IIUM Repository |
| collection | Online Access |
| description | Introduction: Hypertension is the most prevalent risk factor of cardiovascular diseases in Malaysia. 17.3% of hypertension cases in Malaysia is attributed to adults aged 18 to 39 years. Psychosocial distress is a possible risk factor for elevated blood pressure in young adults, and cortisol could be the mediating factor. The aim of this study is to evaluate the mediating role of cortisol in hypertension and psychosocial distress in young adults.
Methods and materials: A comparative cross-sectional study was conducted in 240 young adults aged 45 years or less. The body mass index, waist circumference and blood pressure parameters were recorded. Serum cortisol, creatinine, fasting blood glucose and lipid profile were measured following acute mental stress test. Psychosocial distress was assessed using the DASS-21 questionnaire.
Results: Mean (standard deviation) values for SBP, DBP, MAP were 126.0(16.3), 84.1(12.2) and 98.1(13.1) mmHg respectively. Anxiety was significantly associated with systolic blood pressure (β=0.644), diastolic blood pressure (β=0.454) and mean arterial pressure (β=0.516) after adjusting to sex, age and cortisol. However, it was not mediated by cortisol. Depression and stress were not found to have any effect on blood pressure of the young adults studied.
Conclusion: The data suggests that there is no elevated risk for psychosocial distress and hypertension that cortisol poses in young adults. |
| first_indexed | 2025-11-14T17:31:51Z |
| format | Proceeding Paper |
| id | iium-73872 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T17:31:51Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-738722020-04-15T03:35:42Z http://irep.iium.edu.my/73872/ Psychosocial distress and blood pressure among young adults: role of cortisol as mediator Wan Omar, Wan Fatein Nabeila Musa, Ramli Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah A.Talib, Norlelawati Aung, Sithu Abdullah, Aszrin QP Physiology RC321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System Introduction: Hypertension is the most prevalent risk factor of cardiovascular diseases in Malaysia. 17.3% of hypertension cases in Malaysia is attributed to adults aged 18 to 39 years. Psychosocial distress is a possible risk factor for elevated blood pressure in young adults, and cortisol could be the mediating factor. The aim of this study is to evaluate the mediating role of cortisol in hypertension and psychosocial distress in young adults. Methods and materials: A comparative cross-sectional study was conducted in 240 young adults aged 45 years or less. The body mass index, waist circumference and blood pressure parameters were recorded. Serum cortisol, creatinine, fasting blood glucose and lipid profile were measured following acute mental stress test. Psychosocial distress was assessed using the DASS-21 questionnaire. Results: Mean (standard deviation) values for SBP, DBP, MAP were 126.0(16.3), 84.1(12.2) and 98.1(13.1) mmHg respectively. Anxiety was significantly associated with systolic blood pressure (β=0.644), diastolic blood pressure (β=0.454) and mean arterial pressure (β=0.516) after adjusting to sex, age and cortisol. However, it was not mediated by cortisol. Depression and stress were not found to have any effect on blood pressure of the young adults studied. Conclusion: The data suggests that there is no elevated risk for psychosocial distress and hypertension that cortisol poses in young adults. 2018 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/73872/19/Psychosocial%20Distress%20and%20Blood%20Pressure%20among%20Young%20Adults.pdf Wan Omar, Wan Fatein Nabeila and Musa, Ramli and Ab Rahman, Jamalludin and Mohd Shah, Azarisman Shah and A.Talib, Norlelawati and Aung, Sithu and Abdullah, Aszrin (2018) Psychosocial distress and blood pressure among young adults: role of cortisol as mediator. In: Medical Research Symposium 2018, 9th August 2018, Kuantan, Pahang. (Unpublished) |
| spellingShingle | QP Physiology RC321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System Wan Omar, Wan Fatein Nabeila Musa, Ramli Ab Rahman, Jamalludin Mohd Shah, Azarisman Shah A.Talib, Norlelawati Aung, Sithu Abdullah, Aszrin Psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| title | Psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| title_full | Psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| title_fullStr | Psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| title_full_unstemmed | Psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| title_short | Psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| title_sort | psychosocial distress and blood pressure among young adults: role of cortisol as mediator |
| topic | QP Physiology RC321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System |
| url | http://irep.iium.edu.my/73872/ http://irep.iium.edu.my/73872/19/Psychosocial%20Distress%20and%20Blood%20Pressure%20among%20Young%20Adults.pdf |