Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines

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Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines

The syntheses and bioactivities of symmetrical curcumin and its analogues have been the subject of interest by many medicinal chemists and pharmacologists over the years. To improve our understanding, we have synthesized a series of unsymmetrical monocarbonyl curcumin analogues and evaluated their e...

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Bibliographic Details
Main Authors:	Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Yamin, Bohari M., Leong, Sze Wei, Abdul Bahari, Mohd Nazri, Lim, Sock Jin, Mohd Faudzi, Siti Munirah, Jalil, Juriyati, Abas, Faridah, Mohd Fauzi, Norsyahida, Ismail, Nor Hadiani, Jantan, Ibrahim, Lam, Kok Wai
Format:	Article
Language:	English
Published:	Elsevier 2016
Subjects:	RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:	http://irep.iium.edu.my/73763/ http://irep.iium.edu.my/73763/1/Kamal%20Rullah%2011.pdf

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