A flow cell culture apparatus
Bacterial adhesion is an initial and critical step in the oral colonization process. Adhesion processes may include attachment of the bacterial cell to host cells, to components of the extracellular matrix (ECM), to the salivary pellicle on teeth and to soluble factors, as well as to bacterial cells...
| Main Authors: | , , |
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| Format: | Patent |
| Language: | English English English English |
| Published: |
2018
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| Online Access: | http://irep.iium.edu.my/73637/ http://irep.iium.edu.my/73637/1/20190108%20%286703%29-Filing%20Reporting.pdf http://irep.iium.edu.my/73637/2/Specs%20as%20filed%20%286703%29.pdf http://irep.iium.edu.my/73637/11/Attachment%201%20%28from%20Disclosure%20Form%20V6%29-Mohd%20Hafiz%20Arzmi.pdf http://irep.iium.edu.my/73637/12/3D%20flow%20cell%20mouth%20model.pdf |
| _version_ | 1848787829768847360 |
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| author | Arzmi, Mohd Hafiz Mohd Nasir, Mohd Hamzah Idris, Abdul Halim |
| author_facet | Arzmi, Mohd Hafiz Mohd Nasir, Mohd Hamzah Idris, Abdul Halim |
| author_sort | Arzmi, Mohd Hafiz |
| building | IIUM Repository |
| collection | Online Access |
| description | Bacterial adhesion is an initial and critical step in the oral colonization process. Adhesion processes may include attachment of the bacterial cell to host cells, to components of the extracellular matrix (ECM), to the salivary pellicle on teeth and to soluble factors, as well as to bacterial cells of the same strain (auto-aggregation) or genetically distinct species (co-aggregation).
The oral biofilm formation and development, and the inside selection of specific microorganisms have been correlated with oral diseases, such as dental caries, periodontal disease and oral candidiasis. Many of these microorganisms are oral microbiome, that, in particular situations, can express their virulence factors. A better understanding on the mechanisms of these pathologies is necessary in order to elucidate the complex interactions between microorganisms in the biofilm niche and host tissues. Therefore, it is desirable that an apparatus is designed to reproduce the oral environment for in-vitro cell culture study purpose. |
| first_indexed | 2025-11-14T17:31:09Z |
| format | Patent |
| id | iium-73637 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English English |
| last_indexed | 2025-11-14T17:31:09Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-736372019-08-29T07:57:59Z http://irep.iium.edu.my/73637/ A flow cell culture apparatus Arzmi, Mohd Hafiz Mohd Nasir, Mohd Hamzah Idris, Abdul Halim QR Microbiology RK Dentistry Bacterial adhesion is an initial and critical step in the oral colonization process. Adhesion processes may include attachment of the bacterial cell to host cells, to components of the extracellular matrix (ECM), to the salivary pellicle on teeth and to soluble factors, as well as to bacterial cells of the same strain (auto-aggregation) or genetically distinct species (co-aggregation). The oral biofilm formation and development, and the inside selection of specific microorganisms have been correlated with oral diseases, such as dental caries, periodontal disease and oral candidiasis. Many of these microorganisms are oral microbiome, that, in particular situations, can express their virulence factors. A better understanding on the mechanisms of these pathologies is necessary in order to elucidate the complex interactions between microorganisms in the biofilm niche and host tissues. Therefore, it is desirable that an apparatus is designed to reproduce the oral environment for in-vitro cell culture study purpose. 2018-12-28 Patent NonPeerReviewed application/pdf en http://irep.iium.edu.my/73637/1/20190108%20%286703%29-Filing%20Reporting.pdf application/pdf en http://irep.iium.edu.my/73637/2/Specs%20as%20filed%20%286703%29.pdf application/pdf en http://irep.iium.edu.my/73637/11/Attachment%201%20%28from%20Disclosure%20Form%20V6%29-Mohd%20Hafiz%20Arzmi.pdf application/pdf en http://irep.iium.edu.my/73637/12/3D%20flow%20cell%20mouth%20model.pdf Arzmi, Mohd Hafiz and Mohd Nasir, Mohd Hamzah and Idris, Abdul Halim (2018) A flow cell culture apparatus. PI2018003016. PI2018003016 |
| spellingShingle | QR Microbiology RK Dentistry Arzmi, Mohd Hafiz Mohd Nasir, Mohd Hamzah Idris, Abdul Halim A flow cell culture apparatus |
| title | A flow cell culture apparatus |
| title_full | A flow cell culture apparatus |
| title_fullStr | A flow cell culture apparatus |
| title_full_unstemmed | A flow cell culture apparatus |
| title_short | A flow cell culture apparatus |
| title_sort | flow cell culture apparatus |
| topic | QR Microbiology RK Dentistry |
| url | http://irep.iium.edu.my/73637/ http://irep.iium.edu.my/73637/ http://irep.iium.edu.my/73637/1/20190108%20%286703%29-Filing%20Reporting.pdf http://irep.iium.edu.my/73637/2/Specs%20as%20filed%20%286703%29.pdf http://irep.iium.edu.my/73637/11/Attachment%201%20%28from%20Disclosure%20Form%20V6%29-Mohd%20Hafiz%20Arzmi.pdf http://irep.iium.edu.my/73637/12/3D%20flow%20cell%20mouth%20model.pdf |