Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives

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Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives

Some new 3H-quinazolin-4-one derivatives were synthesised and screened for anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities. Compound 15d was more potent in reducing the cell viabilities of HT-29 and SW620 cells lines to 38%, 36.7%, compared to 5-FU which demonstr...

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Bibliographic Details
Main Authors:	El-Sayed, Nahed Nasser Eid, Almaneai, Norah M., Ben Bacha, Abir G., Al-Obeed, Omar A., Ahmad, Rehan, Abdulla, Maha Hamadien, Alafeefy, Ahmed Mahmoud
Format:	Article
Language:	English English English
Published:	Taylor & Francis 2019
Subjects:	QD Chemistry RC254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/72704/ http://irep.iium.edu.my/72704/19/72704_Synthesis%20and%20evaluation%20of%20anticancer_article.pdf http://irep.iium.edu.my/72704/2/72704_Synthesis%20and%20evaluation%20of%20anticancer_scopus.pdf http://irep.iium.edu.my/72704/3/72704_Synthesis%20and%20evaluation%20of%20anticancer_wos.pdf

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