Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations
Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the thyroid gland and generally biologically indolent. Prognosis of the cancer is excelle...
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| Format: | Article |
| Language: | English English English |
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Ivyspring International Publisher
2019
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| Online Access: | http://irep.iium.edu.my/72650/ http://irep.iium.edu.my/72650/1/72650_Papillary%20Thyroid%20Cancer.pdf http://irep.iium.edu.my/72650/2/72650_Papillary%20Thyroid%20Cancer_SCOPUS.pdf http://irep.iium.edu.my/72650/13/72650_Papillary%20Thyroid%20Cancer_wos.pdf |
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| author | Abdullah, Mardiaty Iryani Mat Junit, Sarni Khoon, Leong Ng Jayapalan, Jaime Jacqueline Karikalan, Barani Hashim, Onn |
| author_facet | Abdullah, Mardiaty Iryani Mat Junit, Sarni Khoon, Leong Ng Jayapalan, Jaime Jacqueline Karikalan, Barani Hashim, Onn |
| author_sort | Abdullah, Mardiaty Iryani |
| building | IIUM Repository |
| collection | Online Access |
| description | Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid.
It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the
thyroid gland and generally biologically indolent. Prognosis of the cancer is excellent, with less than 2%
mortality at 5 years. However, more than 25% of patients with PTC developed a recurrence during a long
term follow-up. The present article provides an updated condensed overview of PTC, which focuses
mainly on the molecular alterations involved and recent biomarker investigations. |
| first_indexed | 2025-11-14T17:28:21Z |
| format | Article |
| id | iium-72650 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T17:28:21Z |
| publishDate | 2019 |
| publisher | Ivyspring International Publisher |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-726502020-04-02T03:58:34Z http://irep.iium.edu.my/72650/ Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations Abdullah, Mardiaty Iryani Mat Junit, Sarni Khoon, Leong Ng Jayapalan, Jaime Jacqueline Karikalan, Barani Hashim, Onn RC254 Neoplasms. Tumors. Oncology (including Cancer) Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the thyroid gland and generally biologically indolent. Prognosis of the cancer is excellent, with less than 2% mortality at 5 years. However, more than 25% of patients with PTC developed a recurrence during a long term follow-up. The present article provides an updated condensed overview of PTC, which focuses mainly on the molecular alterations involved and recent biomarker investigations. Ivyspring International Publisher 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/72650/1/72650_Papillary%20Thyroid%20Cancer.pdf application/pdf en http://irep.iium.edu.my/72650/2/72650_Papillary%20Thyroid%20Cancer_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/72650/13/72650_Papillary%20Thyroid%20Cancer_wos.pdf Abdullah, Mardiaty Iryani and Mat Junit, Sarni and Khoon, Leong Ng and Jayapalan, Jaime Jacqueline and Karikalan, Barani and Hashim, Onn (2019) Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations. International Journal of Medical Sciences, 16 (3). pp. 450-460. ISSN 1449-1907 http://www.medsci.org/v16p0450.pdf 10.7150/ijms.29935 |
| spellingShingle | RC254 Neoplasms. Tumors. Oncology (including Cancer) Abdullah, Mardiaty Iryani Mat Junit, Sarni Khoon, Leong Ng Jayapalan, Jaime Jacqueline Karikalan, Barani Hashim, Onn Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations |
| title | Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations |
| title_full | Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations |
| title_fullStr | Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations |
| title_full_unstemmed | Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations |
| title_short | Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations |
| title_sort | papillary thyroid cancer: genetic alterations and molecular biomarker investigations |
| topic | RC254 Neoplasms. Tumors. Oncology (including Cancer) |
| url | http://irep.iium.edu.my/72650/ http://irep.iium.edu.my/72650/ http://irep.iium.edu.my/72650/ http://irep.iium.edu.my/72650/1/72650_Papillary%20Thyroid%20Cancer.pdf http://irep.iium.edu.my/72650/2/72650_Papillary%20Thyroid%20Cancer_SCOPUS.pdf http://irep.iium.edu.my/72650/13/72650_Papillary%20Thyroid%20Cancer_wos.pdf |