Investigation of porcupine bezoar extract combined with electroporation on HeLa cell

Current chemo-preventive agents will causes a long term side effects in cancer sufferer. Therefore, this research focusses on the benefits of combine both technique of Electroporation (EP) method and with natural animal extract in process to inhibit the proliferation of cancer cell, as a soluti...

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Main Authors: Azizulkarim, Azra Hazwanie, Abdul Jamil, Muhammad Mahadi, Tengku Ibrahim, Tengku Nadzlin, Hamdan, Salehhuddin, Baba, Sayang, Abdul Wahab, Ridhwan
Format: Proceeding Paper
Language:English
English
Published: Institute of Electrical and Electronics Engineers Inc. 2019
Subjects:
Online Access:http://irep.iium.edu.my/72648/
http://irep.iium.edu.my/72648/2/72648_Investigation%20of%20porcupine%20bezoar_complete.pdf
http://irep.iium.edu.my/72648/1/72648_Investigation%20of%20porcupine%20bezoar_scopus.pdf
_version_ 1848787653093228544
author Azizulkarim, Azra Hazwanie
Abdul Jamil, Muhammad Mahadi
Tengku Ibrahim, Tengku Nadzlin
Hamdan, Salehhuddin
Baba, Sayang
Abdul Wahab, Ridhwan
author_facet Azizulkarim, Azra Hazwanie
Abdul Jamil, Muhammad Mahadi
Tengku Ibrahim, Tengku Nadzlin
Hamdan, Salehhuddin
Baba, Sayang
Abdul Wahab, Ridhwan
author_sort Azizulkarim, Azra Hazwanie
building IIUM Repository
collection Online Access
description Current chemo-preventive agents will causes a long term side effects in cancer sufferer. Therefore, this research focusses on the benefits of combine both technique of Electroporation (EP) method and with natural animal extract in process to inhibit the proliferation of cancer cell, as a solution to reduce or adverse effects of orthodox drugs. The present study indicates on anti-cancer potentially of Porcupine Bezoar Extract (PBE), also known as Hystrix Brachyuran against HeLa cell. Cell viability of HeLa cell were determined after HeLa cell treated with 500 V/cm and pulse duration of 100µs before the concentration of 80.0 µg/ml of Porcupine Bezoar Extract (PBE) was added into the cell. The cell viability and cell growth were monitored up to 48 hours with comparative to untreated cell as a control group.This study result proved that by combine both technique; Electroporation (EP) and with natural animal extract Porcupine Bezoar Extract (PBE) might open the door and it has an ability in supressing the growth of HeLa cell.
first_indexed 2025-11-14T17:28:21Z
format Proceeding Paper
id iium-72648
institution International Islamic University Malaysia
institution_category Local University
language English
English
last_indexed 2025-11-14T17:28:21Z
publishDate 2019
publisher Institute of Electrical and Electronics Engineers Inc.
recordtype eprints
repository_type Digital Repository
spelling iium-726482019-06-14T09:04:22Z http://irep.iium.edu.my/72648/ Investigation of porcupine bezoar extract combined with electroporation on HeLa cell Azizulkarim, Azra Hazwanie Abdul Jamil, Muhammad Mahadi Tengku Ibrahim, Tengku Nadzlin Hamdan, Salehhuddin Baba, Sayang Abdul Wahab, Ridhwan QP Physiology R Medicine (General) RM Therapeutics. Pharmacology T Technology (General) TP Chemical technology Current chemo-preventive agents will causes a long term side effects in cancer sufferer. Therefore, this research focusses on the benefits of combine both technique of Electroporation (EP) method and with natural animal extract in process to inhibit the proliferation of cancer cell, as a solution to reduce or adverse effects of orthodox drugs. The present study indicates on anti-cancer potentially of Porcupine Bezoar Extract (PBE), also known as Hystrix Brachyuran against HeLa cell. Cell viability of HeLa cell were determined after HeLa cell treated with 500 V/cm and pulse duration of 100µs before the concentration of 80.0 µg/ml of Porcupine Bezoar Extract (PBE) was added into the cell. The cell viability and cell growth were monitored up to 48 hours with comparative to untreated cell as a control group.This study result proved that by combine both technique; Electroporation (EP) and with natural animal extract Porcupine Bezoar Extract (PBE) might open the door and it has an ability in supressing the growth of HeLa cell. Institute of Electrical and Electronics Engineers Inc. 2019-04-08 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/72648/2/72648_Investigation%20of%20porcupine%20bezoar_complete.pdf application/pdf en http://irep.iium.edu.my/72648/1/72648_Investigation%20of%20porcupine%20bezoar_scopus.pdf Azizulkarim, Azra Hazwanie and Abdul Jamil, Muhammad Mahadi and Tengku Ibrahim, Tengku Nadzlin and Hamdan, Salehhuddin and Baba, Sayang and Abdul Wahab, Ridhwan (2019) Investigation of porcupine bezoar extract combined with electroporation on HeLa cell. In: 8th IEEE International Conference on Control System, Computing and Engineering, ICCSCE 2018, 23-25 November 2018, PARKROYAL Penang Resort Batu Ferringhi Penang. https://ieeexplore.ieee.org/document/8685005 10.1109/ICCSCE.2018.8685005
spellingShingle QP Physiology
R Medicine (General)
RM Therapeutics. Pharmacology
T Technology (General)
TP Chemical technology
Azizulkarim, Azra Hazwanie
Abdul Jamil, Muhammad Mahadi
Tengku Ibrahim, Tengku Nadzlin
Hamdan, Salehhuddin
Baba, Sayang
Abdul Wahab, Ridhwan
Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
title Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
title_full Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
title_fullStr Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
title_full_unstemmed Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
title_short Investigation of porcupine bezoar extract combined with electroporation on HeLa cell
title_sort investigation of porcupine bezoar extract combined with electroporation on hela cell
topic QP Physiology
R Medicine (General)
RM Therapeutics. Pharmacology
T Technology (General)
TP Chemical technology
url http://irep.iium.edu.my/72648/
http://irep.iium.edu.my/72648/
http://irep.iium.edu.my/72648/
http://irep.iium.edu.my/72648/2/72648_Investigation%20of%20porcupine%20bezoar_complete.pdf
http://irep.iium.edu.my/72648/1/72648_Investigation%20of%20porcupine%20bezoar_scopus.pdf