Influence of artocarpus altilis fruit extract on cancer cell
Conventional chemopreventive agents causes adverse side effects in cancer patients. Thus, this study focuses on the effects of natural plant extract against cancer cell as a way to reduce or detrimental effects of orthodox drugs. The present study emphasizes on anti-cancer potentiality of Artocarpus...
| Main Authors: | , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
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Institute of Electrical and Electronics Engineers Inc.
2019
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| Online Access: | http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/1/72557_Influence%20of%20artocarpus%20altilis%20fruit.pdf http://irep.iium.edu.my/72557/2/72557_Influence%20of%20artocarpus%20altilis%20fruit_SCOPUS.pdf |
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| author | Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan |
| author_facet | Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan |
| author_sort | Ganeson, Suhassni |
| building | IIUM Repository |
| collection | Online Access |
| description | Conventional chemopreventive agents causes adverse side effects in cancer patients. Thus, this study focuses on the effects of natural plant extract against cancer cell as a way to reduce or detrimental effects of orthodox drugs. The present study emphasizes on anti-cancer potentiality of Artocarpus altilis fruit extract against cervical cancer cell. Cervical cancer cell treated with methanol extract of artocarpus altilis fruit with the concentration varied from 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50μg/ml. Treated and untreated (cells without treatment) cell proliferation and half maximal inhibitory concentration IC50 measured after 72 hours of incubation. Cells without treatment, 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50 μg/ml of extract concentration showed 1.3, 0.98, 0.72, 0.65, 0.51, and 0.3 of cell proliferation factor accordingly with 40μg/ml of IC50 value. The result shows that artocarpus altilis is capable in opposing cervical cancer cell proliferation or growth as the proliferation factor decreases with the increasing dose of extract concentration which can be attributed to the presence of bioactive compound in Artocarpus altilis. |
| first_indexed | 2025-11-14T17:28:02Z |
| format | Proceeding Paper |
| id | iium-72557 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:28:02Z |
| publishDate | 2019 |
| publisher | Institute of Electrical and Electronics Engineers Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-725572019-06-12T03:22:16Z http://irep.iium.edu.my/72557/ Influence of artocarpus altilis fruit extract on cancer cell Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan R Medicine (General) RC254 Neoplasms. Tumors. Oncology (including Cancer) Conventional chemopreventive agents causes adverse side effects in cancer patients. Thus, this study focuses on the effects of natural plant extract against cancer cell as a way to reduce or detrimental effects of orthodox drugs. The present study emphasizes on anti-cancer potentiality of Artocarpus altilis fruit extract against cervical cancer cell. Cervical cancer cell treated with methanol extract of artocarpus altilis fruit with the concentration varied from 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50μg/ml. Treated and untreated (cells without treatment) cell proliferation and half maximal inhibitory concentration IC50 measured after 72 hours of incubation. Cells without treatment, 10μg/ml, 20μg/ml, 30μg/ml, 40μg/ml and 50 μg/ml of extract concentration showed 1.3, 0.98, 0.72, 0.65, 0.51, and 0.3 of cell proliferation factor accordingly with 40μg/ml of IC50 value. The result shows that artocarpus altilis is capable in opposing cervical cancer cell proliferation or growth as the proliferation factor decreases with the increasing dose of extract concentration which can be attributed to the presence of bioactive compound in Artocarpus altilis. Institute of Electrical and Electronics Engineers Inc. 2019-03-01 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/72557/1/72557_Influence%20of%20artocarpus%20altilis%20fruit.pdf application/pdf en http://irep.iium.edu.my/72557/2/72557_Influence%20of%20artocarpus%20altilis%20fruit_SCOPUS.pdf Ganeson, Suhassni and Abdul Jamil, Muhammad Mahadi and Ambar, Radzi and Abdul Wahab, Ridhwan (2019) Influence of artocarpus altilis fruit extract on cancer cell. In: 9th IEEE Control and System Graduate Research Colloquium (ICSGRC 2018), 3rd-4th Aug. 2018, Shah Alam, Selangor. https://ieeexplore.ieee.org/document/8657520 10.1109/ICSGRC.2018.8657520 |
| spellingShingle | R Medicine (General) RC254 Neoplasms. Tumors. Oncology (including Cancer) Ganeson, Suhassni Abdul Jamil, Muhammad Mahadi Ambar, Radzi Abdul Wahab, Ridhwan Influence of artocarpus altilis fruit extract on cancer cell |
| title | Influence of artocarpus altilis fruit extract on cancer cell |
| title_full | Influence of artocarpus altilis fruit extract on cancer cell |
| title_fullStr | Influence of artocarpus altilis fruit extract on cancer cell |
| title_full_unstemmed | Influence of artocarpus altilis fruit extract on cancer cell |
| title_short | Influence of artocarpus altilis fruit extract on cancer cell |
| title_sort | influence of artocarpus altilis fruit extract on cancer cell |
| topic | R Medicine (General) RC254 Neoplasms. Tumors. Oncology (including Cancer) |
| url | http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/ http://irep.iium.edu.my/72557/1/72557_Influence%20of%20artocarpus%20altilis%20fruit.pdf http://irep.iium.edu.my/72557/2/72557_Influence%20of%20artocarpus%20altilis%20fruit_SCOPUS.pdf |