Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

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Inhibition of prostaglandin E-2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation

The discovery of potent inhibitors of prostaglandin E2 (PGE2) synthesis in recent years has been proven to be an important game changer in pharmaceutical industry. It is known that excessive production of PGE2 triggers a vast array of biological signals and physiological events that contributes to...

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Bibliographic Details
Main Authors:	Kamal, Rullah, Mohd Aluwi, Mohd Fadhlizil Fasihi, M. Yamin, Bohari, Abdul Bahari, Mohd Nazri, Sze Wei, Leong, Ahmad, Syahida, Abas, Faridah, Ismail, Nor Hadiani, Jantan, Ibrahim, Lam, Kok Wai
Format:	Article
Language:	English
Published:	Elsevier 2014
Subjects:	QD Chemistry RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:	http://irep.iium.edu.my/72070/ http://irep.iium.edu.my/72070/1/Paper%20BMCL%20%28full%29.pdf

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