GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves

Natural resources especially plants give great opportunities for alternative treatment of many diseases. The interests in herbal or plant medicines have been increasing in recent years due to their efficacy and cost-effectiveness (Ekor, 2014). Piper betle L. or known as ‘Sireh’ in Malaysia has been...

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Main Authors: Mohammad, Mardhiah, Mohd Azlan, Mawaddah
Format: Proceeding Paper
Language:English
Published: 2019
Subjects:
Online Access:http://irep.iium.edu.my/71862/
http://irep.iium.edu.my/71862/1/Poster%20melaka%202018%201.pdf
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author Mohammad, Mardhiah
Mohd Azlan, Mawaddah
author_facet Mohammad, Mardhiah
Mohd Azlan, Mawaddah
author_sort Mohammad, Mardhiah
building IIUM Repository
collection Online Access
description Natural resources especially plants give great opportunities for alternative treatment of many diseases. The interests in herbal or plant medicines have been increasing in recent years due to their efficacy and cost-effectiveness (Ekor, 2014). Piper betle L. or known as ‘Sireh’ in Malaysia has been useful in treating various conditions including wound injuries, conjunctivitis, constipation, bronchitis, and asthma (Hossain et al, 2017). Therefore, this study was aimed to investigate the phytochemical compounds present in Piper betle L. methanolic extraction using Gas Chromatography-Mass Spectrometry (GCMS) and Liquid Chromatography-Mass Spectrometry (LCMS) analyses. First, the leaves of the plant were grounded into powder and consecutively soaked in methanol for 15 days. The mixture was then filtered and converted to concentrate using rotary evaporator before been subjected to analyses. GCMS and LCMS have identified 10 and 26 compounds respectively. ‘Phenols’ was identified as a major component of the extract in both analyses. Additional compounds such as ‘Cassiaside’, ‘Samarcandin’ and ‘Sesamoside’ were identified by LCMS. The results exhibited compounds with medicinal properties such as antioxidant, anti-inflammatory, and anti-cancer properties. This study has discovered the presence of phytocomponents with therapeutic importance, which can further be studied and be used in future treatments.
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institution International Islamic University Malaysia
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spelling iium-718622019-07-03T07:03:28Z http://irep.iium.edu.my/71862/ GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves Mohammad, Mardhiah Mohd Azlan, Mawaddah Q Science (General) R Medicine (General) Natural resources especially plants give great opportunities for alternative treatment of many diseases. The interests in herbal or plant medicines have been increasing in recent years due to their efficacy and cost-effectiveness (Ekor, 2014). Piper betle L. or known as ‘Sireh’ in Malaysia has been useful in treating various conditions including wound injuries, conjunctivitis, constipation, bronchitis, and asthma (Hossain et al, 2017). Therefore, this study was aimed to investigate the phytochemical compounds present in Piper betle L. methanolic extraction using Gas Chromatography-Mass Spectrometry (GCMS) and Liquid Chromatography-Mass Spectrometry (LCMS) analyses. First, the leaves of the plant were grounded into powder and consecutively soaked in methanol for 15 days. The mixture was then filtered and converted to concentrate using rotary evaporator before been subjected to analyses. GCMS and LCMS have identified 10 and 26 compounds respectively. ‘Phenols’ was identified as a major component of the extract in both analyses. Additional compounds such as ‘Cassiaside’, ‘Samarcandin’ and ‘Sesamoside’ were identified by LCMS. The results exhibited compounds with medicinal properties such as antioxidant, anti-inflammatory, and anti-cancer properties. This study has discovered the presence of phytocomponents with therapeutic importance, which can further be studied and be used in future treatments. 2019-01-01 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/71862/1/Poster%20melaka%202018%201.pdf Mohammad, Mardhiah and Mohd Azlan, Mawaddah (2019) GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves. In: The 15th Symposium of The Malaysian Society of Applied Biology (MSAB) 2018, 29th June - 1st July 2018, Melaka. http://msabsimposium.blogspot.com/p/technical-session.html
spellingShingle Q Science (General)
R Medicine (General)
Mohammad, Mardhiah
Mohd Azlan, Mawaddah
GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves
title GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves
title_full GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves
title_fullStr GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves
title_full_unstemmed GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves
title_short GCMS and LCMS analyses of phytochemical compound in methanolic extract of Piper betle leaves
title_sort gcms and lcms analyses of phytochemical compound in methanolic extract of piper betle leaves
topic Q Science (General)
R Medicine (General)
url http://irep.iium.edu.my/71862/
http://irep.iium.edu.my/71862/
http://irep.iium.edu.my/71862/1/Poster%20melaka%202018%201.pdf