Global metabolic analyses of acinetobacter baumannii
Acinetobacter baumannii is rapidly emerging as a multidrug-resistant pathogen responsible for nosocomial infections including pneumonia, bacteremia, wound infections, urinary tract infections, and meningitis. Metabolomics provides a powerful tool to gain a system-wide snapshot of cellular biochemica...
| Main Authors: | , , , |
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| Format: | Book Chapter |
| Language: | English English |
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Humana Press
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/71260/ http://irep.iium.edu.my/71260/1/71260_Global%20Metabolic%20Analyses%20of%20Acinetobacter%20baumannii.pdf http://irep.iium.edu.my/71260/7/71260_Global%20metabolic%20analyses%20of%20acinetobacter_scopus.pdf |
| _version_ | 1848787427347398656 |
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| author | Mahamad Maifiah, Mohd Hafidz Velkov, Tony Creek, Darren J. Li, Jian |
| author_facet | Mahamad Maifiah, Mohd Hafidz Velkov, Tony Creek, Darren J. Li, Jian |
| author_sort | Mahamad Maifiah, Mohd Hafidz |
| building | IIUM Repository |
| collection | Online Access |
| description | Acinetobacter baumannii is rapidly emerging as a multidrug-resistant pathogen responsible for nosocomial infections including pneumonia, bacteremia, wound infections, urinary tract infections, and meningitis. Metabolomics provides a powerful tool to gain a system-wide snapshot of cellular biochemical networks under defined conditions and has been increasingly applied to bacterial physiology and drug discovery. Here we describe an optimized sample preparation method for untargeted metabolomics studies in A. baumannii. Our method provides a significant recovery of intracellular metabolites to demonstrate substantial differences in global metabolic profiles among A. baumannii strains. |
| first_indexed | 2025-11-14T17:24:45Z |
| format | Book Chapter |
| id | iium-71260 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:24:45Z |
| publishDate | 2019 |
| publisher | Humana Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-712602019-07-12T04:24:32Z http://irep.iium.edu.my/71260/ Global metabolic analyses of acinetobacter baumannii Mahamad Maifiah, Mohd Hafidz Velkov, Tony Creek, Darren J. Li, Jian QR Microbiology RM300 Drugs and their action Acinetobacter baumannii is rapidly emerging as a multidrug-resistant pathogen responsible for nosocomial infections including pneumonia, bacteremia, wound infections, urinary tract infections, and meningitis. Metabolomics provides a powerful tool to gain a system-wide snapshot of cellular biochemical networks under defined conditions and has been increasingly applied to bacterial physiology and drug discovery. Here we describe an optimized sample preparation method for untargeted metabolomics studies in A. baumannii. Our method provides a significant recovery of intracellular metabolites to demonstrate substantial differences in global metabolic profiles among A. baumannii strains. Humana Press 2019 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/71260/1/71260_Global%20Metabolic%20Analyses%20of%20Acinetobacter%20baumannii.pdf application/pdf en http://irep.iium.edu.my/71260/7/71260_Global%20metabolic%20analyses%20of%20acinetobacter_scopus.pdf Mahamad Maifiah, Mohd Hafidz and Velkov, Tony and Creek, Darren J. and Li, Jian (2019) Global metabolic analyses of acinetobacter baumannii. In: Acinetobacter baumannii. Humana Press, New York, pp. 321-328. ISBN 978-1-4939-9117-4 https://experiments.springernature.com/articles/10.1007/978-1-4939-9118-1_28 |
| spellingShingle | QR Microbiology RM300 Drugs and their action Mahamad Maifiah, Mohd Hafidz Velkov, Tony Creek, Darren J. Li, Jian Global metabolic analyses of acinetobacter baumannii |
| title | Global metabolic analyses of acinetobacter baumannii |
| title_full | Global metabolic analyses of acinetobacter baumannii |
| title_fullStr | Global metabolic analyses of acinetobacter baumannii |
| title_full_unstemmed | Global metabolic analyses of acinetobacter baumannii |
| title_short | Global metabolic analyses of acinetobacter baumannii |
| title_sort | global metabolic analyses of acinetobacter baumannii |
| topic | QR Microbiology RM300 Drugs and their action |
| url | http://irep.iium.edu.my/71260/ http://irep.iium.edu.my/71260/ http://irep.iium.edu.my/71260/1/71260_Global%20Metabolic%20Analyses%20of%20Acinetobacter%20baumannii.pdf http://irep.iium.edu.my/71260/7/71260_Global%20metabolic%20analyses%20of%20acinetobacter_scopus.pdf |