Metabolic responses to polymyxin treatment in acinetobacter baumannii ATCC 19606: integrating transcriptomics and metabolomics with genome-scale metabolic modeling
Multidrug-resistant (MDR) Acinetobacter baumannii has emerged as a very problematic pathogen over the past decades, with a high incidence in nosocomial infections. Discovered in the late 1940s but abandoned in the 1970s, polymyxins (i.e., polymyxin B and colistin) have been revived as the last-line...
| Main Authors: | Zhu, Yan, Zhao, Jinxin, Mahamad Maifiah, Mohd Hafidz, Velkov, Tony, Schreiber, Falk, Lia, Jian |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
American Society for Microbiology
2019
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/70940/ http://irep.iium.edu.my/70940/7/70940_Metabolic%20Responses%20to%20Polymyxin_wos.pdf http://irep.iium.edu.my/70940/13/70940_%20Metabolic%20responses%20to%20polymyxin%20treatment%20in%20acinetobacter%20baumannii%20ATCC%2019606.pdf |
Similar Items
Global metabolic analyses of acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2019)
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2019)
Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2016)
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2016)
Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa
by: Zhu, Yan, et al.
Published: (2018)
by: Zhu, Yan, et al.
Published: (2018)
Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2017)
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2017)
Treatment outcomes of patients with acinetobacter infection : comparison between polymyxin versus non polymyxin based therapy
by: Jeeawoody, Aakil
Published: (2019)
by: Jeeawoody, Aakil
Published: (2019)
Pharmacodynamics of colistin against Acinetobacter baumannii
by: Mohd Rasidin, Rashizal Sazli
Published: (2017)
by: Mohd Rasidin, Rashizal Sazli
Published: (2017)
Quorum sensing and surface attachment in Acinetobacter baumannii
by: Lopez Martin, Mario
Published: (2020)
by: Lopez Martin, Mario
Published: (2020)
Metabolic capability of Acinetobacter baumannii based on phenotype microarray analysis and the effects of selected substrates on its biofilm forming ability / Ahlam Hodaed Alsheikh
by: Ahlam Hodaed , Alsheikh
Published: (2018)
by: Ahlam Hodaed , Alsheikh
Published: (2018)
Acinetobacter baumanniiphenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis
by: Bhuiyan, Md Saruar, et al.
Published: (2016)
by: Bhuiyan, Md Saruar, et al.
Published: (2016)
Demonstration Of Antigenic And Specific Outer Membrane Protein(S) Of Acinetobacter Baumannii
by: Shafiqul Islam, A.H.M.
Published: (2009)
by: Shafiqul Islam, A.H.M.
Published: (2009)
Revisiting an ‘old’ antibiotic class polymyxins by drug combination therapy targeting Gram-negative superbugs: Toyyiban perspective
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2019)
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2019)
Demonstration of antigenic and specific surface association heat shock protein(s) of acinetobacter baumannii
by: Hasnur, Nur Nadhra Adila
Published: (2018)
by: Hasnur, Nur Nadhra Adila
Published: (2018)
Overview: metabolomics and lipidomics in nutrition and metabolism research.
by: Newsholme, Philip
Published: (2016)
by: Newsholme, Philip
Published: (2016)
Delineating the plausible molecular vaccine candidates and drug targets of multidrug-resistant Acinetobacter baumannii
by: Mujawar, Shama *, et al.
Published: (2019)
by: Mujawar, Shama *, et al.
Published: (2019)
Phenotypic and molecular characterisation of clinical carbapenem-resistant acinetobacter baumannii / Kong Boon Hong
by: Kong, Boon Hong
Published: (2012)
by: Kong, Boon Hong
Published: (2012)
Acinetobacter baumannii strain 6.1 16S ribosomal RNA gene, partial sequence
by: Kamarudin, Kamarul Rahim, et al.
Published: (2012)
by: Kamarudin, Kamarul Rahim, et al.
Published: (2012)
The mazEF toxin-antitoxin system as a novel antibacterial target in Acinetobacter baumannii
by: Ghafourian, Sobhan, et al.
Published: (2014)
by: Ghafourian, Sobhan, et al.
Published: (2014)
Characterization and identification of newly isolated Acinetobacter baumannii strain Serdang 1 for phenol removal
by: Mohamad Yadzir, Zailatul Hani, et al.
Published: (2012)
by: Mohamad Yadzir, Zailatul Hani, et al.
Published: (2012)
Occurrence of multidrug-resistant Acinetobacter baumannii and Escherichia coli in veterinary health care facilities
by: Ng, Joanna Sze Yi
Published: (2015)
by: Ng, Joanna Sze Yi
Published: (2015)
The characterisation of carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae in a teaching hospital in Malaysia
by: Lau, Min Yi, et al.
Published: (2024)
by: Lau, Min Yi, et al.
Published: (2024)
Genome-Wide Metabolic And Evolutionary Analysis Of
Paenibacillus Polymyxa Atcc 15970
by: Sim , Kee Shin
Published: (2015)
by: Sim , Kee Shin
Published: (2015)
Elucidation of Pigment Biosynthetic Pathways – Towards Integration of Metabolomics, Metabolic Flux Analysis, and Metabolic Engineering
by: Kamarudin, Kamarul Rahim, et al.
Published: (2012)
by: Kamarudin, Kamarul Rahim, et al.
Published: (2012)
Genomic adaptation in antimicrobial resistance: Elucidating the route and effects in acinetobacter baumannii / Mohamad Izwan Ismail
by: Ismail, Mohamad Izwan
Published: (2016)
by: Ismail, Mohamad Izwan
Published: (2016)
Genomic adaptation in antimicrobial resistance: elucidating the route and effects in Acinetobacter baumannii / Mohamad Izwan Ismail
by: Ismail, Mohamad Izwan
Published: (2016)
by: Ismail, Mohamad Izwan
Published: (2016)
Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania
by: Akpunarlieva, Snezhana, et al.
Published: (2017)
by: Akpunarlieva, Snezhana, et al.
Published: (2017)
Molecular characterization and comparative genomics of multidrug resistant acinetobacter baumannii from Malaysia / Lean Soo Sum
by: Lean, Soo Sum
Published: (2016)
by: Lean, Soo Sum
Published: (2016)
Unravelling virulence activities of hospital isolated acinetobacter baumannii: exploring the prospective application of aspirin as an antivirulence agent
by: Nurrul Syairah A Shukor,, et al.
Published: (2024)
by: Nurrul Syairah A Shukor,, et al.
Published: (2024)
Occurrence of multidrug-resistant Acinetobacter baumannii and Escherichia coli in veterinary healthcare facilities in Klang Valley, Malaysia
by: Ng, S. Y., et al.
Published: (2016)
by: Ng, S. Y., et al.
Published: (2016)
Molecular epidemiology of multiple drug resistant Acinetobacter baumannii from a major teaching hospital in Malaysia
by: Moghaddam, Mohammad Reza Babaei
Published: (2016)
by: Moghaddam, Mohammad Reza Babaei
Published: (2016)
Characterization of a molybdenum-reducing Acinetobacter baumannii strain Serdang 1 with the capacity to grow on phenol and acrylamide
by: Mohamad Yadzir, Zailatul Hani, et al.
Published: (2016)
by: Mohamad Yadzir, Zailatul Hani, et al.
Published: (2016)
Phenol removal by newly isolated Acinetobacter baumannii strain Serdang 1 in a packed-bed column reactor
by: Mohamad Yadzir, Zailatul Hani, et al.
Published: (2016)
by: Mohamad Yadzir, Zailatul Hani, et al.
Published: (2016)
Antimicrobial susceptibility and
molecular profiles of acinetobacter
baumannii in Makkah hospitals, and the
potential use of bacteriophage as a
treatment option
by: Raees, Fahad
Published: (2022)
by: Raees, Fahad
Published: (2022)
The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism
by: Demetz, E., et al.
Published: (2014)
by: Demetz, E., et al.
Published: (2014)
Investigation of metabolic effects of polymer nanomedicines using advanced metabolomics methods
by: AbuHammad, Ala
Published: (2024)
by: AbuHammad, Ala
Published: (2024)
Supervised identification of Acinetobacter Baumanni strains using artificial neural network
by: Mohd Tamrin, Mohd Izzuddin, et al.
Published: (2019)
by: Mohd Tamrin, Mohd Izzuddin, et al.
Published: (2019)
Effect Of Crude Aldehyde Dehydrogenase
On The Degradation Of Crude Oil By A
Local Isolate, Acinetobacter Baumannii
Fetl C4
by: Chee , Mei Sing
Published: (2010)
by: Chee , Mei Sing
Published: (2010)
Transcriptome analysis of Stagonospora nodorum: gene models, effectors, metabolism and pantothenate dispensability
by: Ipcho, S., et al.
Published: (2011)
by: Ipcho, S., et al.
Published: (2011)
Development of a dna-based method for simultaneous detection of acinetobacter baumannii, antimicrobial resistance genes and its genotypes by dna fingerprinting
by: Ee, Chan Shiao
Published: (2017)
by: Ee, Chan Shiao
Published: (2017)
Antibacterial and antibiofilm
properties of salvadora persica extracts
against carbapenem-resistant acinetobacter
baumannii isolated from endotracheal
tube samples
by: Alias, Wan Alif Syazwani Wan
Published: (2024)
by: Alias, Wan Alif Syazwani Wan
Published: (2024)
Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures
by: Zulak, Katherine, et al.
Published: (2008)
by: Zulak, Katherine, et al.
Published: (2008)
Similar Items
-
Global metabolic analyses of acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2019) -
Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2016) -
Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa
by: Zhu, Yan, et al.
Published: (2018) -
Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii
by: Mahamad Maifiah, Mohd Hafidz, et al.
Published: (2017) -
Treatment outcomes of patients with acinetobacter infection : comparison between polymyxin versus non polymyxin based therapy
by: Jeeawoody, Aakil
Published: (2019)