Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay
Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-diabetic potential through α-amylase and α-...
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| Format: | Article |
| Language: | English |
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Zebline International Publishing
2019
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| Online Access: | http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/1/70806_Anti-diabetic%20potential%20of%20peptide%20from%20P.%20niruri.pdf |
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| author | Md Zin, Noor Hasniza Mohd Nail, Ainul Mardhiah |
| author_facet | Md Zin, Noor Hasniza Mohd Nail, Ainul Mardhiah |
| author_sort | Md Zin, Noor Hasniza |
| building | IIUM Repository |
| collection | Online Access |
| description | Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic
properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were
investigated for their anti-diabetic potential through α-amylase and α-glucosidase enzyme inhibition assays. For the
enzyme inhibition assay, fruit was found to have the highest inhibition percentage (90.0%) against α-glucosidase
followed by leave (62.6%) and stem (38.4%). The similar patterns were also recorded for the α-amylase enzyme
inhibition assay, in which, fruit showed the highest inhibition percentage (64.1%) followed by leave (33.3%) and
stem (18.2%). The findings of this research suggest that fruit of P. niruri is a potential plant part with regards to antidiabetic
properties since it exhibits the highest inhibition activity against both α-amylase and α-glucosidase enzyme
compared to leave and stem. |
| first_indexed | 2025-11-14T17:23:33Z |
| format | Article |
| id | iium-70806 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T17:23:33Z |
| publishDate | 2019 |
| publisher | Zebline International Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-708062019-07-12T08:04:48Z http://irep.iium.edu.my/70806/ Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay Md Zin, Noor Hasniza Mohd Nail, Ainul Mardhiah Q Science (General) Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-diabetic potential through α-amylase and α-glucosidase enzyme inhibition assays. For the enzyme inhibition assay, fruit was found to have the highest inhibition percentage (90.0%) against α-glucosidase followed by leave (62.6%) and stem (38.4%). The similar patterns were also recorded for the α-amylase enzyme inhibition assay, in which, fruit showed the highest inhibition percentage (64.1%) followed by leave (33.3%) and stem (18.2%). The findings of this research suggest that fruit of P. niruri is a potential plant part with regards to antidiabetic properties since it exhibits the highest inhibition activity against both α-amylase and α-glucosidase enzyme compared to leave and stem. Zebline International Publishing 2019-02-14 Article PeerReviewed application/pdf en http://irep.iium.edu.my/70806/1/70806_Anti-diabetic%20potential%20of%20peptide%20from%20P.%20niruri.pdf Md Zin, Noor Hasniza and Mohd Nail, Ainul Mardhiah (2019) Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay. Science Heritage Journal (GWS), 3 (1). pp. 17-19. ISSN 2521-0858 E-ISSN 2521-0866 https://zibelinepub.com/archives/1gws2019/1gws2019-17-19.pdf doi.org/10.26480/gws.01.20198.17.19 |
| spellingShingle | Q Science (General) Md Zin, Noor Hasniza Mohd Nail, Ainul Mardhiah Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| title | Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| title_full | Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| title_fullStr | Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| title_full_unstemmed | Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| title_short | Anti-diabetic potential of peptide from P. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| title_sort | anti-diabetic potential of peptide from p. niruri reveals through carbohydrate hydrolyzing enzyme inhibition assay |
| topic | Q Science (General) |
| url | http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/ http://irep.iium.edu.my/70806/1/70806_Anti-diabetic%20potential%20of%20peptide%20from%20P.%20niruri.pdf |