Analogues of 2-Deoxyglucose as inhibitor candidates for hexokinase II identified via virtual screening analyses

QR Code

Analogues of 2-Deoxyglucose as inhibitor candidates for hexokinase II identified via virtual screening analyses

Dengue fever is one of the major global health issues, yet specific treatment remains vague. The human hexokinase isoform II (HK2) is one of the crucial enzyme for dengue virus (DENV) replication and thus has been suggested as a potential therapeutic target for DENV drug development. In this paper...

Full description

Bibliographic Details
Main Authors:	Tanbin, Suriyea, Ogu Salim, Nurhainis, Ahmad Fuad, Fazia Adyani
Format:	Proceeding Paper
Language:	English
Published:	Kulliyyah of Engineering, International Islamic University Malaysia 2018
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/70506/ http://irep.iium.edu.my/70506/1/70506_Analogues%20of%202-Deoxyglucose%20as%20Inhibitor%20Candidates.pdf

Similar Items

Identifying analogues of 2-deoxyglucose, alpha-d-glucose and beta-d-glucose-6-phosphate as potential inhibitors of human hexokinase ii for the development of anti-dengue therapeutics
by: Tanbin, Suriyea, et al.
Published: (2019)

Expression and purification of soluble bacterially-expressed human hexokinase II in E.coli system
by: Tanbin, Suriyea, et al.
Published: (2019)

Screening potential inhibitors of lactate dehydrogenase from Plasmodium knowlesi via virtual screening approaches
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2017)

Identifying potential inhibitors of human hexokinase II for the development of anti-dengue therapeutics via virtual screening approaches
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2017)

Inhibitors of leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2016)

Inhibitors of Leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies
by: Fazia Adyani Ahmad Fuad,, et al.
Published: (2016)

Plasmodial enzymes in metabolic pathways as therapeutic targets and contemporary strategies to discover new antimalarial drugs: a review
by: Ogu Salim, Nurhainis, et al.
Published: (2019)

Contemporary strategies and current trends in designing antiviral drugs against dengue fever via targeting host-based approaches
by: Ahammad, Foysal, et al.
Published: (2019)

Phosphoglycerate mutase from Trypanosoma brucei is hyperactivated by cobalt in vitro, but not in vivo
by: Ahmad Fuad, Fazia Adyani
Published: (2011)

Multiple oligomeric and conformational states of trypanosomatid phosphoglycerate mutases
by: Ahmad Fuad, Fazia Adyani
Published: (2013)

Characterization of conformational and oligomeric states of proteins
by: Ahmad Fuad, Fazia Adyani
Published: (2018)

Hexokinase and carnitine palmitoyltransferase activities in flight muscles of grasshopper Valanga nigricornis(burm.)
by: Lee, C. W., et al.
Published: (1983)

Potential novel inhibitors of trypanosomatid phosphoglycerate mutases through ligand-based and structure-based in silico approaches
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2015)

Virtual screening for ganodermal polyketide synthases inhibitor
by: Ong, Chia Sui, et al.
Published: (2017)

The synthesis and testing of novel analogues of (+)-ambuic acid as inhibitors of staphylococcal virulence
by: Reekes, James
Published: (2021)

Molecular docking analysis of curcumin analogues as human neutrophil elastase inhibitors
by: Narayanaswamy, Radhakrishnan, et al.
Published: (2014)

Identification of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by an integrated method of pharmacophore virtual screening, docking, QSAR and ADMET analyses
by: Rullah, Kamal, et al.
Published: (2023)

Hexokinase, Malate Dehydrogenase, Fluorescent Esterase and Malic Enzyme Polymorphisms in the Cocoa Pod Borer, Conopomorpha cramerella (Snellen)
by: Tan, Soon Guan, et al.
Published: (1988)

A high-throughput screen to identify novel calcineurin inhibitors
by: Margassery, L., et al.
Published: (2012)

Synthesis, in vitro evaluation, and radiolabeling of fluorinated puromycin analogues: potential candidates for PET imaging of protein synthesis
by: Betts, Helen M., et al.
Published: (2016)

Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxide inhibitors
by: Mohd Faudzi, S. M., et al.
Published: (2015)

Identification Of Potential Neuraminidase Inhibitors Using Ensemble-Based Virtual Screening
by: Lim, Kok Keong
Published: (2013)

The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors
by: Szabo, M., et al.
Published: (2011)

Virtual screening, molecular docking, molecular dynamics, and MM-GBSA approaches identify prospective fructose-1,6-bisphosphatase inhibitors from pineapple for diabetes management
by: Hossain, Md. Sanower, et al.
Published: (2023)

Potential Neuraminidase Inhibitors Via Virtual Screening, Kinetic Studies, And Adme Predictions
by: Nuwarda, Rina Fajri
Published: (2015)

Hierarchical And Fragment Based Virtual Screening Approaches In The Discovery Of Potent Acetylcholinesterase Inhibitor
by: Muhammad, Erma Fatiha
Published: (2022)

Drug susceptibility test for new na-inhibitors candidate for type a influenza viruses
by: Shamsuddin, Shaharum
Published: (2016)

Utilizing Gene Tree Variation to Identify Candidate Effector Genes in Zymoseptoria tritici
by: McDonald, M., et al.
Published: (2016)

Scoping Studies into the Structure-Activity Relationship (SAR) of Phenylephrine-Derived Analogues as Inhibitors of Trypanosoma brucei rhodesiense
by: Cullen, Danica, et al.
Published: (2016)

Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus.
by: See, Ven Lim, et al.
Published: (2011)

Virtual High Throughput Screening For Avian Influenza (H5nl) Neuraminidase Inhibitors
by: Ismail, Nurul Izza
Published: (2011)

Identification of potential riboflavin synthase inhibitors by virtual screening and molecular dynamics simulation studies
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2021)

Genomic analyses identify molecular subtypes of pancreatic cancer
by: Bailey, P., et al.
Published: (2016)

Design, Synthesis and Disposition Studies of New ISRIB Analogues, Targeting eIF2B, as Potential Candidates for enhancing protein synthesis rate
by: Abo Alard, Akeel
Published: (2021)

Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes
by: Melton, Phillip, et al.
Published: (2019)

Simultaneous determination of phosphodiesterase-5 (PDE-5) inhibitors and their analogues in sexual enhancement products / Nur Baizura Bujang
by: Nur Baizura, Bujang
Published: (2018)

Writing essays using e-book writing application: analyses of teacher candidates' interactive narratives
by: Kee, Li Li, et al.
Published: (2022)

High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
by: Tan, Chen Shen
Published: (2015)

A candidate tolerance gene identified in a natural population of field voles (Microtus agrestis)
by: Wanelik, Klara M., et al.
Published: (2018)

Identifying stem cells role in ulcerative colitis by bioinformatic analyses
by: Ordonez Moran, P.
Published: (2024)