Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
INTRODUCTION: There is no consensus on the optimal timing of liver resection in patients with synchronous colorectal liver metastasis. METHODS: Patients undergoing hepatic resections between 2004- 2013 for synchronous colorectal liver metastases were analyzed from a prospectively maintained and...
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| Format: | Article |
| Language: | English |
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Elsevier
2014
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| Online Access: | http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/2/liver%20resection.pdf |
| _version_ | 1848787180771606528 |
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| author | Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet |
| author_facet | Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet |
| author_sort | Elagili, Faisal |
| building | IIUM Repository |
| collection | Online Access |
| description | INTRODUCTION: There is no consensus on the optimal timing of
liver resection in patients with synchronous colorectal liver
metastasis.
METHODS: Patients undergoing hepatic resections between 2004-
2013 for synchronous colorectal liver metastases were analyzed
from a prospectively maintained and institutional review board
approved database. Patients who underwent simultaneous resection
of a colorectal primary and hepatic metastasis in a single operation
(Group I) were case-matched 1:1with patients who underwent
staged operation (Group II) according to age, sex, ASA classification, size of liver lesion and number of liver lesion.
RESULTS: 66 patients (33 Group I, 33 Group II) were matched
from a total cohort of 106 patients with synchronous colorectal
liver metastasis. The patients’ characteristics of both groups were
similar. 62% were male and the mean age was 55.511 years.
Blood loss and duration of surgery did not differ between
simultaneous resections and staged resection (p¼0.63; p¼0.14,
respectively). Perioperative complication rate were similar in both
groups (P¼0.70). There was no mortality. The median number
of in-hospital days during the course of treatment was 9 (4-23)
days in Group I and 6 (3-17) days in Group II (p <0.001). There
was no difference in 2 years disease free survival and overall survival
were found between Group I and Group II ( 30% and 34%, p¼
0.58; 67% and 62%, p¼0.86 respectively).
CONCLUSIONS: Simultaneous liver resections result in similar
short and long eterm outcomes as in patients undergoing sequential resections for synchronous colorectal cancer with comparable
metastatic disease burden. |
| first_indexed | 2025-11-14T17:20:50Z |
| format | Article |
| id | iium-69804 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T17:20:50Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-698042023-07-04T03:28:34Z http://irep.iium.edu.my/69804/ Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet RD Surgery INTRODUCTION: There is no consensus on the optimal timing of liver resection in patients with synchronous colorectal liver metastasis. METHODS: Patients undergoing hepatic resections between 2004- 2013 for synchronous colorectal liver metastases were analyzed from a prospectively maintained and institutional review board approved database. Patients who underwent simultaneous resection of a colorectal primary and hepatic metastasis in a single operation (Group I) were case-matched 1:1with patients who underwent staged operation (Group II) according to age, sex, ASA classification, size of liver lesion and number of liver lesion. RESULTS: 66 patients (33 Group I, 33 Group II) were matched from a total cohort of 106 patients with synchronous colorectal liver metastasis. The patients’ characteristics of both groups were similar. 62% were male and the mean age was 55.511 years. Blood loss and duration of surgery did not differ between simultaneous resections and staged resection (p¼0.63; p¼0.14, respectively). Perioperative complication rate were similar in both groups (P¼0.70). There was no mortality. The median number of in-hospital days during the course of treatment was 9 (4-23) days in Group I and 6 (3-17) days in Group II (p <0.001). There was no difference in 2 years disease free survival and overall survival were found between Group I and Group II ( 30% and 34%, p¼ 0.58; 67% and 62%, p¼0.86 respectively). CONCLUSIONS: Simultaneous liver resections result in similar short and long eterm outcomes as in patients undergoing sequential resections for synchronous colorectal cancer with comparable metastatic disease burden. Elsevier 2014-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/69804/2/liver%20resection.pdf Elagili, Faisal and Ozuner, Gokhan and Berber, Eren and Akyuz, Muhammet and Cem Dural, Ahmet (2014) Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study. Journal of The American College of Surgeons, 219 (4 Supplement). e75-e76. ISSN 1072-7515 https://www.journalacs.org/article/S1072-7515(14)01120-X/pdf 10.1016/j.jamcollsurg.2014.07.584 |
| spellingShingle | RD Surgery Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| title | Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| title_full | Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| title_fullStr | Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| title_full_unstemmed | Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| title_short | Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| title_sort | comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study |
| topic | RD Surgery |
| url | http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/2/liver%20resection.pdf |