Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum
Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp since this genus is a rich source of active secondary metabolites which showed anti-HIV,...
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| Format: | Proceeding Paper |
| Language: | English English English |
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2018
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| Online Access: | http://irep.iium.edu.my/69563/ http://irep.iium.edu.my/69563/1/SKAM31%20PROGRAMME%20BOOK.pdf http://irep.iium.edu.my/69563/2/index.html http://irep.iium.edu.my/69563/8/69563.pdf |
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| author | Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis |
| author_facet | Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis |
| author_sort | Aminudin, Nurul Iman |
| building | IIUM Repository |
| collection | Online Access |
| description | Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp since this genus is a rich source of active secondary metabolites which showed anti-HIV, cytotoxicity and antimicrobial properties. In this study, antibacterial and antioxidant activities of barks and leaves of C. ferrugineum and C. incrassatum were investigated. Cold extraction method employing dichloromethane, ethyl acetate and methanol as solvent was performed. All extracts were tested for their total phenolic content and antioxidant activities by DPPH radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. The methanol extract from the leaves of C. ferrugineum showed the highest TPC value at 122.08 mg GAE/g and the lowest DPPH SC50 value at 11.80 µg/mL. The methanol extract from the barks of C. ferrugineum was found to have the highest FRAP value among all extracts. The antibacterial activity of all extracts was tested by minimum inhibition concentration (MIC) test against Bacillus subtilis, Staphylococcus aureus, Escheria coli and Pseudomonas aeruginosa. Only the dichloromethane extract from bark of C. ferrugineum showed moderate MIC value against Gram positive bacteria, B. subtilis and S. aureus at 125 µg/mL. |
| first_indexed | 2025-11-14T17:20:09Z |
| format | Proceeding Paper |
| id | iium-69563 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English English |
| last_indexed | 2025-11-14T17:20:09Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-695632019-01-30T04:46:15Z http://irep.iium.edu.my/69563/ Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis QD Chemistry Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp since this genus is a rich source of active secondary metabolites which showed anti-HIV, cytotoxicity and antimicrobial properties. In this study, antibacterial and antioxidant activities of barks and leaves of C. ferrugineum and C. incrassatum were investigated. Cold extraction method employing dichloromethane, ethyl acetate and methanol as solvent was performed. All extracts were tested for their total phenolic content and antioxidant activities by DPPH radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. The methanol extract from the leaves of C. ferrugineum showed the highest TPC value at 122.08 mg GAE/g and the lowest DPPH SC50 value at 11.80 µg/mL. The methanol extract from the barks of C. ferrugineum was found to have the highest FRAP value among all extracts. The antibacterial activity of all extracts was tested by minimum inhibition concentration (MIC) test against Bacillus subtilis, Staphylococcus aureus, Escheria coli and Pseudomonas aeruginosa. Only the dichloromethane extract from bark of C. ferrugineum showed moderate MIC value against Gram positive bacteria, B. subtilis and S. aureus at 125 µg/mL. 2018-08-17 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/69563/1/SKAM31%20PROGRAMME%20BOOK.pdf application/pdf en http://irep.iium.edu.my/69563/2/index.html application/pdf en http://irep.iium.edu.my/69563/8/69563.pdf Aminudin, Nurul Iman and Ahmad, Farediah and Bakhtiar, M. Taher and Deny Susanti, Darnis (2018) Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum. In: International Conference of Analytical Sciences (SKAM31), 17th-19th August 2018, Vistana Hotel, Kuantan, Pahang. (Unpublished) |
| spellingShingle | QD Chemistry Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher Deny Susanti, Darnis Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum |
| title | Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum |
| title_full | Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum |
| title_fullStr | Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum |
| title_full_unstemmed | Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum |
| title_short | Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum |
| title_sort | antibacterial and antioxidant activities of extracts from calophyllum ferrugineum and calophyllum incrassatum |
| topic | QD Chemistry |
| url | http://irep.iium.edu.my/69563/ http://irep.iium.edu.my/69563/1/SKAM31%20PROGRAMME%20BOOK.pdf http://irep.iium.edu.my/69563/2/index.html http://irep.iium.edu.my/69563/8/69563.pdf |