pH responsive polymers in drug delivery

Stimuli-responsive polymer or ‘intelligent’ polymer recently emerged as new potential for drug delivery. Some stimuli have been listed such as thermo, light, ultrasound and pH. In this review, one of the stimuli-responsive polymer which is pH responsive been described in brief including the gelling...

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Main Authors: Mutalabisin, Muhammad Fathiy, Chatterjee, Bappaditya, Md. Jaffri, Juliana
Format: Article
Language:English
Published: A and V Publication 2018
Subjects:
Online Access:http://irep.iium.edu.my/69263/
http://irep.iium.edu.my/69263/1/66_RJPT_11_11_2018.pdf
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author Mutalabisin, Muhammad Fathiy
Chatterjee, Bappaditya
Md. Jaffri, Juliana
author_facet Mutalabisin, Muhammad Fathiy
Chatterjee, Bappaditya
Md. Jaffri, Juliana
author_sort Mutalabisin, Muhammad Fathiy
building IIUM Repository
collection Online Access
description Stimuli-responsive polymer or ‘intelligent’ polymer recently emerged as new potential for drug delivery. Some stimuli have been listed such as thermo, light, ultrasound and pH. In this review, one of the stimuli-responsive polymer which is pH responsive been described in brief including the gelling mechanism, common type of polymers, common applications and current challenges. pH responsive polymers have wide applications in drug delivery. The application mainly covers the site specific drug release in different physiological site. However tumor targeting or in situ gellying nature of these polymers are still in ‘proof-of concept’ stage. Therefore there is still need of crucial evaluation of such polymers and their applications. This review would highlight some important aspects of stimuli sensitive polymers focusing pH-sensitivity and recent reported applications.
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spelling iium-692632019-01-03T08:53:33Z http://irep.iium.edu.my/69263/ pH responsive polymers in drug delivery Mutalabisin, Muhammad Fathiy Chatterjee, Bappaditya Md. Jaffri, Juliana RS192 Materia Medica-Pharmaceutical Technology Stimuli-responsive polymer or ‘intelligent’ polymer recently emerged as new potential for drug delivery. Some stimuli have been listed such as thermo, light, ultrasound and pH. In this review, one of the stimuli-responsive polymer which is pH responsive been described in brief including the gelling mechanism, common type of polymers, common applications and current challenges. pH responsive polymers have wide applications in drug delivery. The application mainly covers the site specific drug release in different physiological site. However tumor targeting or in situ gellying nature of these polymers are still in ‘proof-of concept’ stage. Therefore there is still need of crucial evaluation of such polymers and their applications. This review would highlight some important aspects of stimuli sensitive polymers focusing pH-sensitivity and recent reported applications. A and V Publication 2018-11 Article PeerReviewed application/pdf en http://irep.iium.edu.my/69263/1/66_RJPT_11_11_2018.pdf Mutalabisin, Muhammad Fathiy and Chatterjee, Bappaditya and Md. Jaffri, Juliana (2018) pH responsive polymers in drug delivery. Research Journal of Pharmacy and Technology, 11 (11). pp. 5115-5122. ISSN 0974-3618 E-ISSN 0974-360X http://rjptonline.org/AbstractView.aspx?PID=2018-11-11-66 10.5958/0974-360X.2018.00934.4
spellingShingle RS192 Materia Medica-Pharmaceutical Technology
Mutalabisin, Muhammad Fathiy
Chatterjee, Bappaditya
Md. Jaffri, Juliana
pH responsive polymers in drug delivery
title pH responsive polymers in drug delivery
title_full pH responsive polymers in drug delivery
title_fullStr pH responsive polymers in drug delivery
title_full_unstemmed pH responsive polymers in drug delivery
title_short pH responsive polymers in drug delivery
title_sort ph responsive polymers in drug delivery
topic RS192 Materia Medica-Pharmaceutical Technology
url http://irep.iium.edu.my/69263/
http://irep.iium.edu.my/69263/
http://irep.iium.edu.my/69263/
http://irep.iium.edu.my/69263/1/66_RJPT_11_11_2018.pdf