Molecular docking analysis of 6-paradol, Zingerone and Zerumbone against human estrogen receptor alpha (ERɑ)
Molecular docking was done to assess the binding affinity of 6-paradol (6PRD), Zingerone (ZGR) and Zerumbone (ZRB) ligand-ERα complex in comparison to Hydroxytamoxifen (HTMX). Docking results showed that Glu353 and Arg394 active residues forms hydrogen bonding with 6PRD and ZGR. Glu353, Leu387 and...
| Main Authors: | Sharif, Mohd. Faez, Azirudin, Athirah, Saedudin, RD Rohmat, Mohd Yunus, Afdzal, Abdul Hamid, Azzmer Azzar, Kasim, Shahreen |
|---|---|
| Format: | Article |
| Language: | English English English |
| Published: |
Penerbit UTHM
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/68125/ http://irep.iium.edu.my/68125/1/68125_Molecular%20docking%20analysis%20of%206-paradol.pdf http://irep.iium.edu.my/68125/2/68125_Molecular%20docking%20analysis%20of%206-paradol_SCOPUS.pdf http://irep.iium.edu.my/68125/3/68125_Molecular%20docking%20analysis%20of%206-paradol_WOS.pdf |
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