Formulation of dispersed gliclazide powder in polyethylene glycol–polyvinyl caprolactam– polyvinyl acetate grafted copolymer carrier for capsulation and improved dissolution

Formulation of dispersed gliclazide powder in polyethylene glycol–polyvinyl caprolactam– polyvinyl acetate grafted copolymer carrier for capsulation and improved dissolution

Background: Oral bioavailability of gliclazide, a hypoglycemic drug, is hindered by its low aqueous solubility. Improvement of solubility will enhance dissolution rate and in turn the bioavailability. This research aimed to formulate the solid dispersed gliclazide using a novel polyethylene glycol–p...

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Bibliographic Details
Main Authors: Ahmed Mahdi Dukhan, Ather, Mohamad Yusoff, Nursazreen Amalina, Kyaw Oo, May, Sengupta, Pinaki, Doolaanea, Abd Almonem, Aljapairai, Khater Ahmed Saeed, Chatterjee, Bappaditya
Format: Article
Language:English
Published: Association of Pharmaceutical Teachers of India 2018
Subjects:
RS192 Materia Medica-Pharmaceutical Technology
Online Access:http://irep.iium.edu.my/67672/
http://irep.iium.edu.my/67672/1/IJPER_4_18-QC-RD.pdf

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