Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive v...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Malaysian Medical Associations
2011
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| Online Access: | http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/1/Skin_prick_test_MJM.pdf |
| _version_ | 1848776721931698176 |
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| author | Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina |
| author_facet | Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina |
| author_sort | Asha'ari, Zamzil Amin |
| building | IIUM Repository |
| collection | Online Access |
| description | We compared a newer serum specific IgE (SSIgE) test with
skin prick testing (SPT) in the diagnosis of allergy in
Malaysia. Ninety newly diagnosed allergic patients were
enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive values (PPV, NPV) were calculated for SSIgE for each of the common allergens tested. The highest positive results for both SPT and SSIgE were for house dust mite and cat. Compared to SPT, SSIgE showed better sensitivity but poorer specificity, low PPV and good NPV in all the allergens tested. Significant positive correlation was seen between the diameter of wheal and flare of SPT and the SSIgE results. |
| first_indexed | 2025-11-14T14:34:36Z |
| format | Article |
| id | iium-6730 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T14:34:36Z |
| publishDate | 2011 |
| publisher | Malaysian Medical Associations |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-67302011-12-12T04:34:49Z http://irep.iium.edu.my/6730/ Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina RF Otorhinolaryngology We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive values (PPV, NPV) were calculated for SSIgE for each of the common allergens tested. The highest positive results for both SPT and SSIgE were for house dust mite and cat. Compared to SPT, SSIgE showed better sensitivity but poorer specificity, low PPV and good NPV in all the allergens tested. Significant positive correlation was seen between the diameter of wheal and flare of SPT and the SSIgE results. Malaysian Medical Associations 2011-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/6730/1/Skin_prick_test_MJM.pdf Asha'ari, Zamzil Amin and Yusof, Suhaimi and Yusof, Rosnida Azura and Ismail, Rushdan and CYC, Maraina (2011) Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia. Medical Journal of Malaysia, 66 (3). pp. 202-206. ISSN 0300-5283 http://www.e-mjm.org |
| spellingShingle | RF Otorhinolaryngology Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia |
| title | Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia |
| title_full | Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia |
| title_fullStr | Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia |
| title_full_unstemmed | Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia |
| title_short | Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia |
| title_sort | comparison of serum specific ige with skin prick test in the diagnosis of allergy in malaysia |
| topic | RF Otorhinolaryngology |
| url | http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/1/Skin_prick_test_MJM.pdf |