Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
—Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic...
| Main Authors: | , , , , , |
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| Format: | Proceeding Paper |
| Language: | English |
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Faculty of Computer Systems & Software Engineering, Universiti Malaysia Pahang
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/1/67165_Parametric%20Study%20of%20Soxhlet.pdf |
| _version_ | 1848786709640118272 |
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| author | Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed |
| author_facet | Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed |
| author_sort | Alara, Oluwaseun Ruth |
| building | IIUM Repository |
| collection | Online Access |
| description | —Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of
extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then,the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that
the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier
transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters. |
| first_indexed | 2025-11-14T17:13:21Z |
| format | Proceeding Paper |
| id | iium-67165 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T17:13:21Z |
| publishDate | 2018 |
| publisher | Faculty of Computer Systems & Software Engineering, Universiti Malaysia Pahang |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-671652018-10-31T03:40:43Z http://irep.iium.edu.my/67165/ Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed TP155 Chemical engineering —Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then,the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters. Faculty of Computer Systems & Software Engineering, Universiti Malaysia Pahang 2018-08-28 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/67165/1/67165_Parametric%20Study%20of%20Soxhlet.pdf Alara, Oluwaseun Ruth and Abdurahman, Nour Hamid and Abdul Mudalip, Siti Kholijah and Ukaegbu, Chinonso Ishmael and Azhari, Nour Hamid and Kabbashi, Nassereldeen Ahmed (2018) Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves. In: National Conference for Postgraduate Research 2018 (NCONPGR 2018), 28th-29th Aug. 2018, Kuantan, Pahang. http://ncon-pgr.ump.edu.my/index.php/en/download/proceedings-book/file |
| spellingShingle | TP155 Chemical engineering Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Abdul Mudalip, Siti Kholijah Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_full | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_fullStr | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_full_unstemmed | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_short | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_sort | parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| topic | TP155 Chemical engineering |
| url | http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/ http://irep.iium.edu.my/67165/1/67165_Parametric%20Study%20of%20Soxhlet.pdf |