Topical co-delivery of indomethacin and nigella sativa L. essential oil in poly-cappa-caprolactone nanoparticles: in vitro study of anti-inflammatory activity

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Topical co-delivery of indomethacin and nigella sativa L. essential oil in poly-cappa-caprolactone nanoparticles: in vitro study of anti-inflammatory activity

Indomethacin is a potent, nonselective Non-steroidal Antiinflammatory Drug (NSAID) but its low water-solubility precludes its use as topical dosage form. As with other NSAIDs, the systemic delivery is associated with high risk of serious gastrointestinal adverse events including bleeding, ulcera...

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Bibliographic Details
Main Authors:	Badri, Waisudin, Mohamed, Farahidah, Mohd Shafri, Mohd Affendi, El Asbahani, A., Miladi, Karim, Nazari, Qand Agha, Viennet, Celine, Robin, Sophie, Fessi, Hatem, Elaissari, Abdelhamid
Format:	Article
Language:	English
Published:	International Journal of Advanced Research (IJAR) 2018
Subjects:	RM Therapeutics. Pharmacology RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/66791/ http://irep.iium.edu.my/66791/1/443_IJAR%20indomethacin%20microparticles.pdf

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