Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been repo...
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Taylors & Francis
2018
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| Online Access: | http://irep.iium.edu.my/66702/ http://irep.iium.edu.my/66702/7/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf http://irep.iium.edu.my/66702/8/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids%20%20SCOPUS.pdf |
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| author | Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed |
| author_facet | Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed |
| author_sort | Alara, Oluwaseun Ruth |
| building | IIUM Repository |
| collection | Online Access |
| description | The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance. |
| first_indexed | 2025-11-14T17:12:04Z |
| format | Article |
| id | iium-66702 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-14T17:12:04Z |
| publishDate | 2018 |
| publisher | Taylors & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-667022018-10-18T03:03:27Z http://irep.iium.edu.my/66702/ Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed TP155 Chemical engineering The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance. Taylors & Francis 2018 Article PeerReviewed application/pdf en http://irep.iium.edu.my/66702/7/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf application/pdf en http://irep.iium.edu.my/66702/8/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids%20%20SCOPUS.pdf Alara, Oluwaseun Ruth and Abdurahman, Nour Hamid and Ukaegbu, Chinonso Ishmael and Azhari, Nour Hamid and Kabbashi, Nassereldeen Ahmed (2018) Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS. Journal of Liquid Chromatography & Related Technologies. pp. 1-10. ISSN 1082-6076 E-ISSN 520-572X (In Press) https://www.tandfonline.com/doi/abs/10.1080/10826076.2018.1511995?journalCode=ljlc20 10.1080/10826076.2018.1511995 |
| spellingShingle | TP155 Chemical engineering Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title | Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_full | Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_fullStr | Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_full_unstemmed | Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_short | Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_sort | metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from vernonia cinerea leaf using lc-q-tof-ms |
| topic | TP155 Chemical engineering |
| url | http://irep.iium.edu.my/66702/ http://irep.iium.edu.my/66702/ http://irep.iium.edu.my/66702/ http://irep.iium.edu.my/66702/7/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf http://irep.iium.edu.my/66702/8/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids%20%20SCOPUS.pdf |