GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine

QR Code

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine

The life expectancy for pancreatic cancer patients has seen no substantial changes in the last 40 years as very few and mostly just palliative treatments are available. As the five years survival rate remains around 5%, the identification of novel pharmacological targets and development of new thera...

Full description

Bibliographic Details
Main Authors:	Ferro, Riccardo, Adamska, Aleksandra, Lattanzio, Rossano, Mavrommati, Ioanna, Edling, Charlotte E., Ahmad Arifin, Syamsul, Fyffe, Chanse A., Sala, Gianluca, Sacchetto, L., Chiorino, Giovanna, De Laurenzi, Vincenzo, Piantelli, Mauro, Sansom, Owen, Maffucci, Tania, Falasca, Marco
Format:	Article
Language:	English English
Published:	Nature Publishing Group 2018
Subjects:	RM147 Administration of Drugs and Other Therapeutic Agents RM283 Endocrinotheraphy RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/65709/ http://irep.iium.edu.my/65709/1/65709_GPR55%20signalling%20promotes.pdf http://irep.iium.edu.my/65709/2/65709_GPR55%20signalling%20promotes_SCOPUS%20in%20press.pdf

Similar Items

Lysophosphatidylinositol: a novel link between ABC transporters and G-protein-coupled receptors
by: Ruban, Emily L., et al.
Published: (2014)

Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119
by: Ahmad Arifin, Syamsul, et al.
Published: (2018)

Assessment of lipid-lowering therapy prescribing among patients with type 2 Diabetes Mellitus in Malaysian primary care settings
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2017)

Lysophosphatidylinositol signalling and metabolic diseases
by: Ahmad Arifin, Syamsul, et al.
Published: (2016)

Organic arsenical exposures stimulates atheroscleorosis through oxidative stress increase and adhesion molecule expression
by: Ishola, Afeez Adenkule, et al.
Published: (2016)

Effectiveness and prescription pattern of lipid-lowering therapy and its associated factors among patients with type 2 diabetes mellitus in Malaysian primary care settings
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2019)

Statin therapy prescribing for patients with type 2 diabetes mellitus: a review of current evidence and challenges
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2017)

Cinnamtannin B1: a small compound having antidiabetes properties
by: Bakhtiar, M. Taher, et al.
Published: (2009)

Cinnamtannin B1: a small compound having antidiabetes properties
by: Bakhtiar, M. Taher, et al.
Published: (2009)

Evaluation of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus: findings from two Malaysian tertiary hospitals
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2017)

Caring for patients with diabetes during COVID-19 pandemic: Important considerations for pharmacists
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2020)

Effect of cinnamon extract on blood glucose level and pancreas histopathology in diabetic rats
by: Nor Adilah , Abdul Ghani, et al.
Published: (2016)

Patterns of statin therapy prescribing among hospitalized patients with type 2 diabetes mellitus in two Malaysian tertiary hospitals
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2017)

Pharmacist-led academic detailing improves statin therapy prescribing for Malaysian patients with type 2 diabetes: Quasi-experimental design
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2019)

The beneficial effect of coffee consumption in type 2 diabetes mellitus
by: Yusof, Nur Masyitah, et al.
Published: (2018)

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine
by: Ferro, R., et al.
Published: (2018)

Clinical factors affecting minor amputation in diabetic foot diseases at Tengku Ampuan Afzan Hospital, Kuantan
by: Zakaria@Mohamad, Zamzuri, et al.
Published: (2015)

Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)

Are physicians and clinical pharmacists aware and knowledgeable enough about inappropriate prescribing for elderly patients? Findings from Malaysia
by: Akkawi, Muhammad Eid, et al.
Published: (2018)

Non-neurotoxic activity of Malayan krait (Bungarus candidus) venom from Thailand
by: Charoenpitakchai, Mongkon, et al.
Published: (2018)

Studies on the red sea sponge Haliclona sp. for its chemical and cytotoxic properties
by: Al-Massarani, Shaza Mohamed, et al.
Published: (2016)

Patterns of initial opioid prescribing and its association with short and long-term use among opioid naïve patients: Experience from Malaysia
by: Zin, Che Suraya, et al.
Published: (2018)

Investigation of plasma concentrations of IL-6 and IL-10 in short and long-term opioid users with non-cancer pain
by: Zin, Che Suraya, et al.
Published: (2018)

Trends and patterns of analgesic utilization in Malaysia from 2010 to 2016: preference for tramadol
by: Zin, Che Suraya, et al.
Published: (2018)

In vitro evaluation of the effect of Pluchea indica extracts in promoting glucose consumption activity on a liver cell line
by: Suriyah, Wastuti Hidayati, et al.
Published: (2019)

Analysis of drug-related problems identified by future pharmacists in medical wards of tertiary hospitals in the state of Pahang, Malaysia
by: Elnaem, Mohamed Hassan Abdelaziz, et al.
Published: (2019)

Short-term effects of TAF 273 on oestrous cycle and reproductive hormones of normal rats
by: Ahmad, Nur Amalina, et al.
Published: (2015)

The chemopreventive effects of Nigella sativa extract and Thymoquinone in a paternal toxicity study
by: Abdul Samat, Nadia Hanis, et al.
Published: (2015)

Mitochondrial DNA quantity changes in leucocytes of cancer patients on cisplatin and 5-fluorouracil regimen
by: Khaing, Ei Phyo, et al.
Published: (2016)

Safety of the concurrent use of gabapentin and carbamazepine at moderate therapeutic doses
by: Al-Mahmood, Sinan, et al.
Published: (2017)

Prophylactic effects of Nigella sativa extract and thymoquinone against cyclophosphamide-induced sperm head abnormalities and chromatin instability in mice
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Mechanisms of colorectal cancer cell growth and metastasis inhibition by Carp-1 functional mimetic-4
by: Ashour, Abdelkader Elbadawy Abbas, et al.
Published: (2019)

Research on nonsteroidal anti-inflammatory drugs in Malaysia: a bibliometric analysis
by: Zin, Che Suraya, et al.
Published: (2020)

Halal lifestyle and cancer
by: Amid, Azura
Published: (2011)

In vitro study of antifungal activity of Entada spiralis Ridl. crude extract against dermatophytes of superficial skin disease
by: Harun, Aiza, et al.
Published: (2011)

Beyond anticoagulant: heparin as a potential anti-cancer agent
by: Lokwani, Ravi, et al.
Published: (2014)

Significance of palpitation among hypertensive patients receiving captopril
by: Marbut, Mossa M., et al.
Published: (2009)

Analgesic synergism of gabapentin and carbamazepine in rat model of diabetic neuropathic pain
by: Abdullah Al-Mahmood, Sinan Mohammed, et al.
Published: (2016)

Investigation of in vivo antipyretic activity of thottea dependens leaves
by: Ahmed, Qamar Uddin, et al.
Published: (2015)

Knowledge of atrial fibrillation and stroke prevention: development of questionnaire and validation of results
by: Mohamed, Sahimi, et al.
Published: (2017)