Engineering human epidermal growth receptor 2‑Targeting hepatitis B virus core nanoparticles for siRNA delivery in vitro and in vivo

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Engineering human epidermal growth receptor 2‑Targeting hepatitis B virus core nanoparticles for siRNA delivery in vitro and in vivo

Hepatitis B virus core (HBc) particles acquire the capacity to disassemble and reassemble in a controlled manner, allowing entrapment and delivery of drugs and macromolecules to cells. HBc particles are made of 180−240 copies of 21 kDa protein monomers, assembled into 30−34 nm diameter icosahedral...

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Bibliographic Details
Main Authors:	Mohamed Suffian, Izzat Fahimuddin, Wang, Julie Tzu-Wen, Faruqu, Farid Nazer, Benitez, Julio, Nishimura, Yuya, Ogino, Chiaki, Akihiko, Kondo, Al-Jamal, Khuloud
Format:	Article
Language:	English
Published:	American Chemical Society 2018
Subjects:	RM147 Administration of Drugs and Other Therapeutic Agents RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/64619/ http://irep.iium.edu.my/64619/1/acsanm.8b00480.pdf

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