Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics
Immobilized biocatalysts have many advantages in large scale processing such as retention of enzyme or cell, enhanced stability and increased half-life of the enzyme [1] The efficiency of immobilized biocatalyst particles expressed by effectiveness factor play important role in the design and optimi...
| Main Authors: | , |
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| Format: | Proceeding Paper |
| Language: | English |
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Kulliyyah of Engineering International Islamic University Malaysia (IIUM) 50728 Kuala Lumpur Malaysia
2017
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| Online Access: | http://irep.iium.edu.my/63450/ http://irep.iium.edu.my/63450/6/63450_Numerical%20Simulation%20of%20the%20Effects%20of%20Simultaneous%20Internal_complete.pdf |
| _version_ | 1848786034558500864 |
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| author | Jameel, Ahmad Tariq Hoda, Asif |
| author_facet | Jameel, Ahmad Tariq Hoda, Asif |
| author_sort | Jameel, Ahmad Tariq |
| building | IIUM Repository |
| collection | Online Access |
| description | Immobilized biocatalysts have many advantages in large scale processing such as retention of enzyme or cell, enhanced stability and increased half-life of the enzyme [1] The efficiency of immobilized biocatalyst particles expressed by effectiveness factor play important role in the design and optimization of bioreactors. The effectiveness factor can be calculated once concentration profile within the catalyst pellet is obtained by solving the diffusion-reaction model. Complex rate kinetics such as given by Michaelis-Menten equation which represents host of biological reactions requires numerical solutions even for the simplest diffusion-reaction model. The diffusion-reaction model becomes even more involved in the presence of external mass transfer resistance which assumes significance as particle size increases. Different attempts at numerically solving nonlinear reaction-diffusion equation with and without external mass transfer effects have been reported in literature [1-4]. In this paper, we present a new approach based on finite difference method for the numerical simulation of nonlinear reaction-diffusion process in a spherical biocatalyst pellet with external film mass transfer resistance. |
| first_indexed | 2025-11-14T17:02:37Z |
| format | Proceeding Paper |
| id | iium-63450 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T17:02:37Z |
| publishDate | 2017 |
| publisher | Kulliyyah of Engineering International Islamic University Malaysia (IIUM) 50728 Kuala Lumpur Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-634502018-06-26T06:33:56Z http://irep.iium.edu.my/63450/ Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics Jameel, Ahmad Tariq Hoda, Asif TP155 Chemical engineering TP248.13 Biotechnology Immobilized biocatalysts have many advantages in large scale processing such as retention of enzyme or cell, enhanced stability and increased half-life of the enzyme [1] The efficiency of immobilized biocatalyst particles expressed by effectiveness factor play important role in the design and optimization of bioreactors. The effectiveness factor can be calculated once concentration profile within the catalyst pellet is obtained by solving the diffusion-reaction model. Complex rate kinetics such as given by Michaelis-Menten equation which represents host of biological reactions requires numerical solutions even for the simplest diffusion-reaction model. The diffusion-reaction model becomes even more involved in the presence of external mass transfer resistance which assumes significance as particle size increases. Different attempts at numerically solving nonlinear reaction-diffusion equation with and without external mass transfer effects have been reported in literature [1-4]. In this paper, we present a new approach based on finite difference method for the numerical simulation of nonlinear reaction-diffusion process in a spherical biocatalyst pellet with external film mass transfer resistance. Kulliyyah of Engineering International Islamic University Malaysia (IIUM) 50728 Kuala Lumpur Malaysia 2017-08-08 Proceeding Paper PeerReviewed application/pdf en http://irep.iium.edu.my/63450/6/63450_Numerical%20Simulation%20of%20the%20Effects%20of%20Simultaneous%20Internal_complete.pdf Jameel, Ahmad Tariq and Hoda, Asif (2017) Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics. In: 4th International Conference of Mathematical Applications in Engineering 2017 (ICMAE 2017), 08-09 August 2017, Kuala Lumpur, Malaysia. http://www.iium.edu.my/congress/program.pdf |
| spellingShingle | TP155 Chemical engineering TP248.13 Biotechnology Jameel, Ahmad Tariq Hoda, Asif Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics |
| title | Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics |
| title_full | Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics |
| title_fullStr | Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics |
| title_full_unstemmed | Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics |
| title_short | Numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for Simple Michaelis-Menten Kinetics |
| title_sort | numerical simulation of the effects of simultaneous internal and external mass transfer resistances on the performance of the immobilized spherical catalyst pellet for simple michaelis-menten kinetics |
| topic | TP155 Chemical engineering TP248.13 Biotechnology |
| url | http://irep.iium.edu.my/63450/ http://irep.iium.edu.my/63450/ http://irep.iium.edu.my/63450/6/63450_Numerical%20Simulation%20of%20the%20Effects%20of%20Simultaneous%20Internal_complete.pdf |